Protein Alignment KLK5 and CG4053

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_650601.2
• Gene: CG4053 / 42070
• FlyBaseID: FBgn0038482
• Length: 265
• Species: Drosophila melanogaster
• Alignment Length: 255
• Identity: 75/255 - (29%)
• Similarity: 126/255 - (49%)
• Gaps: 23/255 - (9%)

Human    45 GSNQDLGAGAGEDARS--DDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAA 107
            |::.|:..|...|.|.  |   :||:.|.:.:....|:|.::........|..|:::.||:|||.
  Fly    14 GTSIDVTRGKRLDNRKLLD---NRIVGGQEAEDGVAPYQVSIQTIWKTHICSGVILNEQWILTAG 75

Human   108 HCRK----KVFRVRLGHYSLSPVYESGQQMFQGVKSIPHPGYSHP-GHSNDLMLIKLNRRIRPTK 167
            ||..    :..|:.:|   .:...|.||.:|.. :::.|..|..| .::||:.||.:|..|....
  Fly    76 HCALDFSIEDLRIIVG---TNDRLEPGQTLFPD-EALVHCLYDIPYVYNNDIALIHVNESIIFND 136

Human   168 DVRPINVSSHCPSAGTKCLVSGWGTTKSPQVHFPKV--LQCLNISVLSQKRCEDAYPRQ--IDDT 228
            ..:.:.:|...|.||:...::|||   :|:..:|.|  ||.||:::::.:.|.:.:...  ||..
  Fly   137 RTQIVELSREQPPAGSTVTLTGWG---APESSYPTVQYLQTLNLTIIAHEECRERWDFHDGIDIG 198

Human   229 MFCAGDKAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQET 288
            ..|...:.|..:|.||||||::..|.|.|||:|| ..|. ...|.:|.|...:..||:.|
  Fly   199 HICTFTREGEGACSGDSGGPLMWEGKLVGLVNWG-RACG-VGMPDMYANTVYYQDWIRRT 256

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		7/24 (29%)
		Tryp_SPc	66..285	CDD:214473	66/227 (29%)
CG4053	NP_650601.2	Tryp_SPc	35..256	CDD:238113	67/229 (29%)