Protein Alignment KLK5 and CG17475

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_650600.2
• Gene: CG17475 / 42069
• FlyBaseID: FBgn0038481
• Length: 288
• Species: Drosophila melanogaster
• Alignment Length: 287
• Identity: 80/287 - (27%)
• Similarity: 129/287 - (44%)
• Gaps: 37/287 - (12%)

Human    21 LGVTEHVLANNDVSCDHPSNTVPSGSNQDLGAGAGED-------ARSDDSSSRIINGSDCDMHTQ 78
            |||.:.::.....:|..|.:.|..       |...||       |...:..:|:|||.|..:...
  Fly     4 LGVVQILVILLACTCYKPISAVRL-------AQLSEDQLEWISKAEGVNFQNRVINGEDVQLGEA 61

Human    79 PWQAALLLRPNQLYCGAVLVHPQWLLTAAHC----RKKVFRVRLGHYSLSPVYESGQQMFQGVKS 139
            .:|.:|........||..::..:.:||||||    .....||..|    :..||....::...:.
  Fly    62 KYQISLQGMYGGHICGGCIIDERHVLTAAHCVYGYNPTYLRVITG----TVEYEKPDAVYFVEEH 122

Human   140 IPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSAGTKCLVSGWGTTKSPQVHFPKVL 204
            ..|..|:.|.:.||:.||:||..|:..:..:|..:.:...:.||:.|::|||:|:. ....|.:|
  Fly   123 WIHCNYNSPDYHNDIALIRLNDTIKFNEYTQPAELPTAPVANGTQLLLTGWGSTEL-WGDTPDIL 186

Human   205 QCLNISVLSQKRCEDAY-------PRQIDDTMFCAGDKAGRDSCQGDSGGPVVCNGSLQGLVSWG 262
            |...::.:....|::..       |..|     |.....|:.:|.||||||:..||.|.|||:||
  Fly   187 QKAYLTHVVYSTCQEIMNNDPSNGPCHI-----CTLTTGGQGACHGDSGGPLTHNGVLYGLVNWG 246

Human   263 DYPCARPNRPGVYTNLCKFTKWIQETI 289
             ||||. ..|..:.|:..:.:||:..|
  Fly   247 -YPCAL-GVPDSHANVYYYLEWIRSMI 271

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		7/37 (19%)
		Tryp_SPc	66..285	CDD:214473	67/229 (29%)
CG17475	NP_650600.2	Tryp_SPc	50..269	CDD:238113	68/230 (30%)