Protein Alignment KLK5 and CG10405

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_001036717.1
• Gene: CG10405 / 41996
• FlyBaseID: FBgn0038431
• Length: 268
• Species: Drosophila melanogaster
• Alignment Length: 257
• Identity: 85/257 - (33%)
• Similarity: 124/257 - (48%)
• Gaps: 33/257 - (12%)

Human    50 LGAGAGEDARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLY-CGAVLVHPQWLLTAAHC---- 109
            |.|...|.|......|||:||.:......|:|  |.||...:: |||.::...|.:|||||
  Fly    20 LEASRTEAAVPRQPDSRIVNGREATEGQFPYQ--LSLRRQTVHICGASILSSNWAITAAHCIDGH 82

Human   110 --RKKVFRVRLGHYSLSPVYESGQQMFQGVKSI-PHPGYSHPGHSNDLMLIKL--NRRIRPTKDV 169
              :.:.|.:|.|    |.:..||..: |.||:| .||.|.....:.|:.|::.  .....|...|
  Fly    83 EQQPREFTLRQG----SIMRTSGGTV-QPVKAIYKHPAYDRADMNFDVALLRTADGALSLPLGKV 142

Human   170 RPINVSSHCPSAG------TKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCED--AYPRQID 226
            .||.:    |:.|      ...:|||||...:.......||:...:..::|::|.:  .:...:.
  Fly   143 APIRL----PTVGEAISESMPAVVSGWGHMSTSNPVLSSVLKSTTVLTVNQEKCHNDLRHHGGVT 203

Human   227 DTMFCAGDKAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFT--KWIQ 286
            :.||||..: ..|:||||||||:...|:|.|:|||| ..||.|..|||||.|...|  :||:
  Fly   204 EAMFCAAAR-NTDACQGDSGGPISAQGTLIGIVSWG-VGCADPYYPGVYTRLAHPTIRRWIR 263

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		6/17 (35%)
		Tryp_SPc	66..285	CDD:214473	78/238 (33%)
CG10405	NP_001036717.1	Tryp_SPc	36..262	CDD:214473	78/238 (33%)