Protein Alignment KLK5 and Sb

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_476709.1
• Gene: Sb / 41958
• FlyBaseID: FBgn0003319
• Length: 787
• Species: Drosophila melanogaster
• Alignment Length: 307
• Identity: 97/307 - (31%)
• Similarity: 136/307 - (44%)
• Gaps: 59/307 - (19%)

Human    27 VLANNDVSCDHPSNTVPSGSNQDLGA--------------GAGEDARSDDSSSRIINGSDCDMHT 77
            |||.:.:.    :|.:...|..|.||              |....||.:   :||:.|.......
  Fly   497 VLATSGIE----TNEISDSSIPDAGALGHVKTISAARSECGVPTLARPE---TRIVGGKSAAFGR 554

Human    78 QPWQAALLLRPNQLY-------CGAVLVHPQWLLTAAHCRKKV----FRVRLGHYSLSPVYESGQ 131
            .|||.:  :|....:       ||..|::..|:.||.||...:    .|:|:|.|..|.|.|...
  Fly   555 WPWQVS--VRRTSFFGFSSTHRCGGALINENWIATAGHCVDDLLISQIRIRVGEYDFSHVQEQLP 617

Human   132 QMFQGV-KSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHC-PSA-----GTKCLVSG 189
            .:.:|| |.:.||.||...:..||.|:||.:.:.....|.||     | |..     |....|:|
  Fly   618 YIERGVAKKVVHPKYSFLTYEYDLALVKLEQPLEFAPHVSPI-----CLPETDSLLIGMNATVTG 677

Human   190 WGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQ-----IDDTMFCAG-DKAGRDSCQGDSGGP 248
            ||.. |.....|.|||.:::.::|...|:..:.|.     |.|...||| :..|:||||||||||
  Fly   678 WGRL-SEGGTLPSVLQEVSVPIVSNDNCKSMFMRAGRQEFIPDIFLCAGYETGGQDSCQGDSGGP 741

Human   249 VVCNGS-----LQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQ 290
            :.....     |.|::||| ..||..|.|||.|.:.|||.||.|.::
  Fly   742 LQAKSQDGRFFLAGIISWG-IGCAEANLPGVCTRISKFTPWILEHVR 787

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		9/44 (20%)
		Tryp_SPc	66..285	CDD:214473	83/247 (34%)
Sb	NP_476709.1	Tryp_SPc	544..785	CDD:238113	84/249 (34%)