Protein Alignment KLK5 and CG3916

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_650167.1
• Gene: CG3916 / 41484
• FlyBaseID: FBgn0038003
• Length: 267
• Species: Drosophila melanogaster
• Alignment Length: 257
• Identity: 82/257 - (31%)
• Similarity: 119/257 - (46%)
• Gaps: 25/257 - (9%)

Human    50 LGAGAGEDARSDDSSSRIINGSDCDMHTQPWQAALLLRPN---QLYCGAVLVHPQWLLTAAHCRK 111
            |..|..:...|...|...|||......|.|:|.:|.::..   |.:||..:|..|.:||||||.:
  Fly    13 LRQGLADVVTSTTESPTRINGGQRVNETVPFQVSLQMQRRGRWQHFCGGSIVSGQHVLTAAHCME 77

Human   112 KV----FRVRLGHYSLSPVYESGQQMFQGVKSIPHPGYS-HPGHSNDLMLIKLNRRIR-PTKDVR 170
            |:    ..|.:|..:    :::|....:.|....||.|| :|...||:.|:|:....| ...|:.
  Fly    78 KMKVEDVSVVVGTLN----WKAGGLRHRLVTKHVHPQYSMNPRIINDIALVKVTPPFRLERSDIS 138

Human   171 PINVSSHCPSAGTKCLV--SGWGTTKSPQVH---FPKVLQCLNISVLSQKRCEDAYPRQIDDTMF 230
            .|.:.. ....|.|..|  :|||:| ||...   .|..||.||...:|.:.|.....| :.....
  Fly   139 TILIGG-SDRIGEKVPVRLTGWGST-SPSTSSATLPDQLQALNYRTISNEDCNQKGFR-VTRNEI 200

Human   231 CAGDKAGRDSCQGDSGGPVVCNGS---LQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETI 289
            ||....|:.:|.||||||::..|.   |.|:||:|...||: .||.|||.:..|..:|.:.|
  Fly   201 CALAVQGQGACVGDSGGPLIRPGKQPHLVGIVSYGSSTCAQ-GRPDVYTRVSSFLPYISQVI 261

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		4/17 (24%)
		Tryp_SPc	66..285	CDD:214473	76/235 (32%)
CG3916	NP_650167.1	Tryp_SPc	30..257	CDD:214473	76/234 (32%)