Protein Alignment KLK5 and CG17404

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_650165.2
• Gene: CG17404 / 41482
• FlyBaseID: FBgn0038001
• Length: 275
• Species: Drosophila melanogaster
• Alignment Length: 302
• Identity: 84/302 - (27%)
• Similarity: 124/302 - (41%)
• Gaps: 70/302 - (23%)

Human    21 LGVTEHVLANNDVSCDHPSNTVPSGSNQDLGAGAGE-DAR--SDDSSSRIINGSDC--DMHTQPW 80
            :|:||.:|....|:               ||...|. ::|  |..:..||:.|:|.  ..|. |:
  Fly     1 MGLTEQLLLIGVVA---------------LGGVFGRLNSRQPSGYTPHRIVGGADIPPGEHV-PY 49

Human    81 QAALLLRP--NQL-YCGAVLVHPQWLLTAAHC------------------RKKVFRVRLGHYSLS 124
            |.:|..|.  .|: :||..::.|..:||||||                  .:|..|.::..||:.
  Fly    50 QVSLQYRTRGGQMHFCGGSIIAPNRILTAAHCCQGLNASRMSVVAGIRGLNEKGSRSQVLSYSIH 114

Human   125 PVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSAGTKCLVSG 189
            |.|:........|.||..|             :|||.......:.|  :........|....::|
  Fly   115 PKYQELVTSDLAVLSIKPP-------------LKLNNSTISAIEYR--SQGKDFVGGGVPVTLTG 164

Human   190 WGTTKSP-------QVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDSCQGDSGG 247
            || .:.|       .|::|.|||.::...:|...|.:|....:.||..||.... |.:|.|||||
  Fly   165 WG-LRLPVPFPFLDNVNYPNVLQRMSYHTISNSECRNAGMESVTDTEICARGPF-RGACSGDSGG 227

Human   248 PVVC---NGSLQ-GLVSWGDYPCARPNRPGVYTNLCKFTKWI 285
            |:|.   ||..| |:||:|...|.....|.|||.:..|:.||
  Fly   228 PLVMESKNGLQQVGIVSYGLVVCGLYISPDVYTRVSTFSDWI 269

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		6/33 (18%)
		Tryp_SPc	66..285	CDD:214473	72/252 (29%)
CG17404	NP_650165.2	Tryp_SPc	34..269	CDD:214473	72/252 (29%)