Protein Alignment KLK5 and CG12951

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_649880.1
• Gene: CG12951 / 41110
• FlyBaseID: FBgn0037677
• Length: 265
• Species: Drosophila melanogaster
• Alignment Length: 269
• Identity: 73/269 - (27%)
• Similarity: 119/269 - (44%)
• Gaps: 41/269 - (15%)

Human    46 SNQDLGAG---------AGEDARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQ 101
            |||||...         .|:.|   .|.||::||:|..:...|:..:|........||..::...
  Fly     3 SNQDLSLSLIVILAVTTVGQAA---PSISRVVNGTDSSVLKYPFVVSLRSYDGSHSCGGSIISKH 64

Human   102 WLLTAAHCRK----KVFRVRLGHYSLSPVYESGQQMFQGVKSIPHPGYSHP-GHSNDLMLIKLNR 161
            :::|||||..    ....::.|..::|.:   |..:....|.|.|..:... .::||:.|:.:.
  Fly    65 FVMTAAHCTNGRPADTLSIQFGVTNISAM---GPNVVGIKKIIQHEDFDPTRQNANDISLLMVE- 125

Human   162 RIRPTK----DVRPINVSSHC-----PSAGTKCLVSGWG---TTKSPQVHFPKVLQCLNISVLSQ 214
              .|.:    .|.|:.:.:..     ..||.:.::.|||   |..|.|    ..||.:::.:.|.
  Fly   126 --EPFEFDGVSVAPVELPALAFAVPQSDAGVEGVLIGWGLNDTYGSVQ----DTLQEVSLKIYSD 184

Human   215 KRCEDAYPRQIDDTM-FCAG-DKAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTN 277
            :.|...:..|.|... .|.| |:.|:..|.||||||::.||...|:|||...||.....||||..
  Fly   185 EECTSRHNGQTDPKYHICGGVDEGGKGQCSGDSGGPLIYNGQQVGIVSWSIKPCTVAPYPGVYCK 249

Human   278 LCKFTKWIQ 286
            :.::..||:
  Fly   250 VSQYVDWIK 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		10/30 (33%)
		Tryp_SPc	66..285	CDD:214473	62/237 (26%)
CG12951	NP_649880.1	Tryp_SPc	30..260	CDD:238113	63/239 (26%)