DRSC/TRiP Functional Genomics Resources

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Protein Alignment KLK5 and CG9372

DIOPT Version :10

Sequence 1:NP_036559.1 Gene:KLK5 / 25818 HGNCID:6366 Length:293 Species:Homo sapiens
Sequence 2:NP_649132.1 Gene:CG9372 / 40137 FlyBaseID:FBgn0036891 Length:408 Species:Drosophila melanogaster


Alignment Length:238 Identity:77/238 - (32%)
Similarity:123/238 - (51%) Gaps:26/238 - (10%)


- Green bases have known domain annotations that are detailed below.


Human    66 RIINGSDCDMHTQPWQAALLLRPNQ-LYCGAVLVHPQWLLTAAHC-----RKKVFRVRLGHYSLS 124
            |:..|...:....||.||||..... ::||.||:..:.:||||||     ::.:| ||||.|:..
  Fly   173 RLTGGRPAEPDEWPWMAALLQEGLPFVWCGGVLITDRHVLTAAHCIYKKNKEDIF-VRLGEYNTH 236

Human   125 PVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRR------IRPTKDVRPINVSSHCPSAGT 183
            .:.|:..:.|:....:.|..|:...:.||:.:::::|.      |.|. .:.|:|..    .:..
  Fly   237 MLNETRARDFRIANMVLHIDYNPQNYDNDIAIVRIDRATIFNTYIWPV-CMPPVNED----WSDR 296

Human   184 KCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAG-DKAGRDSCQGDSGG 247
            ..:|:||||.|....| ..:|..:|:.|..|..|..::.:.:.||..||| .:.|:|||||||||
  Fly   297 NAIVTGWGTQKFGGPH-SNILMEVNLPVWKQSDCRSSFVQHVPDTAMCAGFPEGGQDSCQGDSGG 360

Human   248 PVVCNGSLQ-----GLVSWGDYPCARPNRPGVYTNLCKFTKWI 285
            |::.....|     |:|||| ..|.:..|||:||.:.::..||
  Fly   361 PLLVQLPNQRWVTIGIVSWG-VGCGQRGRPGIYTRVDRYLDWI 402

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
KLK5NP_036559.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 37..68 1/1 (100%)
Tryp_SPc 66..285 CDD:214473 75/236 (32%)
CG9372NP_649132.1 CLIP 87..132 CDD:197829
Tryp_SPc 173..402 CDD:214473 75/236 (32%)
Blue background indicates that the domain is not in the aligned region.

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