Protein Alignment KLK5 and CG6865

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_001246825.1
• Gene: CG6865 / 40050
• FlyBaseID: FBgn0036817
• Length: 285
• Species: Drosophila melanogaster
• Alignment Length: 266
• Identity: 77/266 - (28%)
• Similarity: 124/266 - (46%)
• Gaps: 60/266 - (22%)

Human    66 RIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHC---------RKKVFRVRLGHY 121
            :|:.||:.:.:..|:..:|:.|... :||..::..:|:|||.||         :....:..:|.:
  Fly    34 KIVGGSEAERNEMPYMVSLMRRGGH-FCGGTIISERWILTAGHCICNGLQQFMKPAQIQGVVGLH 97

Human   122 SLSPVYESGQQMFQGVKS------------IPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINV 174
            |:       ::...|:.:            :|||.|......:|:.|::|         |:||..
  Fly    98 SI-------REYLNGIGNGPDALRVDFKNIVPHPQYDCNDVKHDIALLEL---------VQPIRF 146

Human   175 SSHC-PSA-----GTKCL------VSGWGTTKSPQVHFPK--VLQCLNISVLSQKRCEDAY---- 221
            |||. ||.     |.:.|      |||||.|...|....:  ||:...:.:.:.:.||.:|
  Fly   147 SSHIQPSCVGSEEGHRSLEQEYGTVSGWGWTHENQAENDRSDVLRKATVKIWNNEACERSYRSLG 211

Human   222 -PRQIDDTMFCAGDKAGR-DSCQGDSGGPVVC-NGSLQGLVSWGDYPCARPNRPGVYTNLCKFTK 283
             ...|.:|..|||.:.|: |||..|||||::. ...|.|:||.| ..||||..||:||.:.|:..
  Fly   212 KSNTIGETQLCAGYENGQIDSCWADSGGPLMSKEHHLVGVVSTG-IGCARPGLPGIYTRVSKYVS 275

Human   284 WIQETI 289
            |:|:.|
  Fly   276 WMQKVI 281

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		0/1 (0%)
		Tryp_SPc	66..285	CDD:214473	74/260 (28%)
CG6865	NP_001246825.1	Tryp_SPc	34..276	CDD:214473	74/259 (29%)