Protein Alignment KLK5 and CG4914

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_648711.1
• Gene: CG4914 / 39597
• FlyBaseID: FBgn0036436
• Length: 374
• Species: Drosophila melanogaster
• Alignment Length: 347
• Identity: 109/347 - (31%)
• Similarity: 152/347 - (43%)
• Gaps: 81/347 - (23%)

Human     2 ATARPPWMWVLCALITAL-----LLGVTEHVL--------------ANNDVSCDHP--------- 38
            ||:.||......:.::::     .||...|..              ||..|...:|
  Fly    36 ATSAPPATSTATSSLSSIPGKYQALGAAHHQAKKLKIGDVNASSSDANKPVFRQNPIKNWFGAFN 100

Human    39 SNTVPSGSNQ---DLGAGAGEDARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHP 100
            .|..|:..||   ......||  |:|:  |||:.|:...:...||.|.|... |:.|||..|::.
  Fly   101 RNNSPAAQNQTSPTCSCRCGE--RNDE--SRIVGGTTTGVSEYPWMARLSYF-NRFYCGGTLIND 160

Human   101 QWLLTAAHCRKK----VFRVRLGHYSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNR 161
            :::||||||.|.    :.:|..|.:......|..:..|  |.......:|.....||:.|::||.
  Fly   161 RYVLTAAHCVKGFMWFMIKVTFGEHDRCNDKERPETRF--VLRAFSQKFSFSNFDNDIALLRLND 223

Human   162 RIRPTKDVRPINVSSHC-PS--------AGTKCLVSGWGTTK---SPQVHFPKVLQCLNISVLSQ 214
            |:..|..:|||     | |.        .|||.:.:||||.|   .|..    :||.:.:.||..
  Fly   224 RVPITSFIRPI-----CLPRVEQRQDLFVGTKAIATGWGTLKEDGKPSC----LLQEVEVPVLDN 279

Human   215 KRC--EDAY-PRQIDDTMFCAG--DKAGRDSCQGDSGGPVVCNGSLQ---------GLVSWGDYP 265
            ..|  :..| .:.|...|.|:|  ...||||||||||||:|   .|:         |:||||: .
  Fly   280 DECVAQTNYTQKMITKNMMCSGYPGVGGRDSCQGDSGGPLV---RLRPDDKRFEQIGIVSWGN-G 340

Human   266 CARPNRPGVYTNLCKFTKWIQE 287
            |||||.|||||.:.|:..||.|
  Fly   341 CARPNYPGVYTRVTKYLDWIVE 362

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		11/42 (26%)
		Tryp_SPc	66..285	CDD:214473	86/248 (35%)
CG4914	NP_648711.1	Tryp_SPc	128..363	CDD:238113	88/251 (35%)