Protein Alignment KLK5 and CG4613

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_648707.2
• Gene: CG4613 / 39586
• FlyBaseID: FBgn0036427
• Length: 374
• Species: Drosophila melanogaster
• Alignment Length: 327
• Identity: 100/327 - (30%)
• Similarity: 157/327 - (48%)
• Gaps: 61/327 - (18%)

Human     2 ATARPPWMWVLCALITALLLGVTEHVLAN-NDVSCDHPSNTVPSGSNQDLGA---------GAGE 56
            :|..||  .|....|..|:.|..:.:|:| ..|:.:.||:|..|..:..|.:         |.|.
  Fly    54 STGPPP--GVQSDFIDDLIEGHKQQILSNVLGVASETPSDTASSLGSTSLSSSASPVFPLEGGGA 116

Human    57 DA-RSDDSSS---------RIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHC-- 109
            .| |.:..:|         ||:.|:....:..|| .|.::|...|:||..|::.:::||||||
  Fly   117 KAFRVNRCASCTCGVPNVNRIVGGTQVRTNKYPW-IAQIIRGTFLFCGGTLINDRYVLTAAHCVH 180

Human   110 --RKKVFRVRLGHYSLSPVYESGQQMFQGV-KSI----PHPGYSHPGHSNDLMLIKLNRRIRPTK 167
              ..:...|||.....|..:       .|| :|:    .|.||......:|:.|::|::.|....
  Fly   181 GMDMRGVSVRLLQLDRSSTH-------LGVTRSVAFAHAHVGYDPVSLVHDIALLRLDQPIPLVD 238

Human   168 DVRPINVSSHCPS--AGTKCLVSGW------GTTKSPQVHFPKVLQCLNISVLSQKRCE-DAYPR 223
            .:||..:.|:...  ...|.:|:||      |:|.|       |||.:.:.:::..:|. .:|..
  Fly   239 TMRPACLPSNWLQNFDFQKAIVAGWGLSQEGGSTSS-------VLQEVVVPIITNAQCRATSYRS 296

Human   224 QIDDTMFCAG--DKAGRDSCQGDSGGPVVCNG---SLQGLVSWGDYPCARPNRPGVYTNLCKFTK 283
            .|.|||.|||  ...|||:||||||||::...   .|.|:||:| |.||:|:.|||||.:.::.:
  Fly   297 MIVDTMMCAGYVKTGGRDACQGDSGGPLIVRDRIFRLAGVVSFG-YGCAKPDAPGVYTRVSRYLE 360

Human   284 WI 285
            ||
  Fly   361 WI 362

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		11/49 (22%)
		Tryp_SPc	66..285	CDD:214473	78/241 (32%)
CG4613	NP_648707.2	Tryp_SPc	136..362	CDD:214473	78/241 (32%)