Protein Alignment KLK5 and CG10663

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_001097592.1
• Gene: CG10663 / 39421
• FlyBaseID: FBgn0036287
• Length: 748
• Species: Drosophila melanogaster
• Alignment Length: 261
• Identity: 77/261 - (29%)
• Similarity: 125/261 - (47%)
• Gaps: 34/261 - (13%)

Human    54 AGEDARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRL 118
            :|...||..:..:||.|........|||.|:|.|..:.:||..|:.|:|:||||||.:||..||:
  Fly   494 SGTGRRSMSNMLKIIGGRAARKGEWPWQVAILNRFKEAFCGGTLIAPRWVLTAAHCVRKVLFVRI 558

Human   119 GHYSLSPVYESGQQM-FQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTK-----------DVRP 171
            |.::|:  ||.|.:: .:.:||..||.:......:|:.|::|.:.:..|.           ...|
  Fly   559 GEHNLN--YEDGTEIQLRVMKSYTHPNFDKRTVDSDVALLRLPKAVNATTWIGYSCLPQPFQALP 621

Human   172 INVSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDA-YPRQIDDTMFCAGDK 235
            .||.         |.:.|||..::.......||....:.::..:.|... |...|...|||||.:
  Fly   622 KNVD---------CTIIGWGKRRNRDATGTSVLHKATVPIIPMQNCRKVYYDYTITKNMFCAGHQ 677

Human   236 AGR-DSCQGDSGGPVVCNGSLQ--------GLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQA 291
            .|. |:|.||||||::|..:.:        |:.|:|| .||:.|:.|:|..:..:..|:...:..
  Fly   678 KGHIDTCAGDSGGPLLCRDTTKPNHPWTIFGITSFGD-GCAQRNKFGIYAKVPNYVDWVWSVVNC 741

Human   292 N 292
            :
  Fly   742 D 742

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		3/13 (23%)
		Tryp_SPc	66..285	CDD:214473	73/240 (30%)
CG10663	NP_001097592.1	Tryp_SPc	506..735	CDD:214473	73/240 (30%)