DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment KLK5 and CG4477

DIOPT Version :10

Sequence 1:NP_036559.1 Gene:KLK5 / 25818 HGNCID:6366 Length:293 Species:Homo sapiens
Sequence 2:NP_648295.1 Gene:CG4477 / 39058 FlyBaseID:FBgn0035971 Length:315 Species:Drosophila melanogaster


Alignment Length:218 Identity:55/218 - (25%)
Similarity:91/218 - (41%) Gaps:31/218 - (14%)


- Green bases have known domain annotations that are detailed below.


Human    92 YCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLSPVYESGQQMFQGVKSIPHPGYSHP-------- 148
            :|..|::.|.:::|:|||.....||.:....|..|..:    ...:|.||:..:..|        
  Fly    71 FCSGVILAPMFVMTSAHCLINKRRVLISSRVLLIVAGT----LNRLKYIPNRTFVTPVTHIWLPD 131

Human   149 ----GHSNDLMLIKL-NRRIRPTKDVRPINVSSHCPSAGTKCLVSGWGT--TKSPQVHFPKVLQC 206
                .:..|..|:|: |...|..:.:....:..|.|..|.||.|.|||.  ...|...:   :..
  Fly   132 SFTMRNKQDFGLLKVKNPFPRNNEHISIARLPVHPPLPGLKCKVMGWGRMYKGGPLASY---MLY 193

Human   207 LNISVLSQKRCEDAYPRQIDDTMFCA---GDKAGRDSCQGDSGGPVVCNGSLQGLVS--WGDYPC 266
            :::.|:..:.|. .:.|.......||   .|...:..|.||.|.|::.||::.|:|:  .|   |
  Fly   194 IDVQVIDSEACA-KWLRVPSVEHVCAVDSDDLTAQQPCGGDWGAPMLHNGTVYGIVTILAG---C 254

Human   267 ARPNRPGVYTNLCKFTKWIQETI 289
            ...:.|.:|||:.....||.|.|
  Fly   255 GVSHLPSLYTNVHSNANWIHEKI 277

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
KLK5NP_036559.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 37..68
Tryp_SPc 66..285 CDD:214473 51/212 (24%)
CG4477NP_648295.1 Tryp_SPc 55..276 CDD:238113 53/215 (25%)
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.