Protein Alignment KLK5 and CG32374

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_729270.1
• Gene: CG32374 / 38848
• FlyBaseID: FBgn0052374
• Length: 299
• Species: Drosophila melanogaster
• Alignment Length: 283
• Identity: 55/283 - (19%)
• Similarity: 87/283 - (30%)
• Gaps: 99/283 - (34%)

Human    40 DEILAATMRPPE---KKKVDQL-NAAHYS-----TGKVSASFTSTAMVP-------ETTHEAAVI 88
            |:.:...:..|.   ||.::.| |.|..|     ..|.:|......::|       ||.|..:..
  Fly   179 DQSITCDISSPRRQVKKSINLLKNLAGASIRADPKNKKAAGIMLLTLLPFVLVTFSETFHIKSWD 243

Human    89 DEDVL--------------RYQFVKKKGYVR-LHTNKGDLNLELHCDL---TPKT-------CEN 128
            |..||              .|.:..|...|: |...|.:|..|:|..|   :|::       |:.
  Fly   244 DNMVLVTLIFSGSATVLYFVYLYFDKADQVKSLEYAKFELMSEVHKHLQNFSPQSLIRNGQLCQE 308

Human   129 FIKLCKKQY---YDGTIFHRSIRNFVIQGG----------------------------DPTGTGT 162
            .:|...|::   .||.|....:::..:..|                            |.|....
  Fly   309 SLKSLFKKFDVNKDGKIQVSELKDLTVDFGVLGRVKCDINELATTLLADFDSNRDGEIDETEFAI 373

Human   163 GGESFWGKPFKDEFRPNLSH-----TGRGVLSMANSGPNTNKSQFFITFRSCAY---LDKK---- 215
            |.|. |.|.:|..|....|.     ...|||.:..            ..:.|.:   |.|:
  Fly   374 GIEK-WLKQYKFSFNGTESQGEDIAEDDGVLKVEQ------------LLKGCLFTKLLTKRTLKA 425

Human   216 --HTIFGRVVGGFDTLTAMENVE 236
              ..|.|..:..|..:..|.|:|
  Fly   426 VIEVIIGITIVSFLAMPFMMNIE 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		8/36 (22%)
		Tryp_SPc	66..285	CDD:214473	47/248 (19%)
CG32374	NP_729270.1	Tryp_SPc	73..292	CDD:214473	25/112 (22%)