Protein Alignment KLK5 and CG10469

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_648025.1
• Gene: CG10469 / 38696
• FlyBaseID: FBgn0035678
• Length: 267
• Species: Drosophila melanogaster
• Alignment Length: 256
• Identity: 79/256 - (30%)
• Similarity: 124/256 - (48%)
• Gaps: 43/256 - (16%)

Human    61 DDSSSRIINGSDCDMHTQPWQAALLL-------RPNQLYCGAVLVHPQWLLTAAHC----RKKVF 114
            :..|.||:||:.......|:|..||.       .||.  ||..::..:|::|||||    :..::
  Fly    18 ETGSLRIMNGTAAKAKQLPYQVGLLCYFEGSKDEPNM--CGGTILSNRWIITAAHCLQDPKSNLW 80

Human   115 RVRLGHYSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCP 179
            :| |.|......::..:.:.....:|.|..:.....:||:.||||.:::...|.::|..:    |
  Fly    81 KV-LIHVGKVKSFDDKEIVVNRSYTIVHKKFDRKTVTNDIALIKLPKKLTFNKYIQPAKL----P 140

Human   180 SA-----GTKCLVSGWG-TTKS-PQVHFPKVLQCLNISVLSQKRCEDAYPRQ--------IDDTM 229
            ||     |.|.::|||| |||. |.    :|||.:...::|.|.||..:.:|        :.:..
  Fly   141 SAKKTYTGRKAIISGWGLTTKQLPS----QVLQYIRAPIISNKECERQWNKQLGGKSKKVVHNGF 201

Human   230 FCAGDKAGRDSCQGDSGGPVVC-NGS--LQGLVSWG-DYPCARPNRPGVYTNLCKFTKWIQ 286
            .|...|.|. .|:||||||:|. :||  |.|:||.| |..| :...|.|.|.:..:.|||:
  Fly   202 ICIDSKKGL-PCRGDSGGPMVLDDGSRTLVGIVSHGFDGEC-KLKLPDVSTRVSSYLKWIK 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		2/6 (33%)
		Tryp_SPc	66..285	CDD:214473	76/248 (31%)
CG10469	NP_648025.1	Tryp_SPc	23..259	CDD:214473	76/248 (31%)