Protein Alignment KLK5 and CG10472

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_648017.1
• Gene: CG10472 / 38688
• FlyBaseID: FBgn0035670
• Length: 290
• Species: Drosophila melanogaster
• Alignment Length: 299
• Identity: 82/299 - (27%)
• Similarity: 127/299 - (42%)
• Gaps: 46/299 - (15%)

Human    13 CA--LITALLLG---VTEHVLANNDVSCDHP---SNTVPSGSNQDLGAGAGEDARSDDSSSRIIN 69
            ||  |:.|.:||   |..:.:.|.::....|   ..|:|||                    ||..
  Fly     5 CATVLLLATILGAQAVDWNSVKNLNIETPMPKVHGETLPSG--------------------RITG 49

Human    70 GSDCDMHTQPWQAALLL--RPNQLYCGAVLVHPQWLLTAAHCRKKV---FRVRLGHYSLSPVYES 129
            |...:.:..|:|..|||  .....:||..::..:|::|||||...:   ..|.||.:..:...|.
  Fly    50 GQIAEPNQFPYQVGLLLYITGGAAWCGGTIISDRWIITAAHCTDSLTTGVDVYLGAHDRTNAKEE 114

Human   130 GQQ-MFQGVKS-IPHPGYSHPGHSNDLMLIKL------NRRIRPTKDVRPINVSSHCPSAGTKCL 186
            ||| :|...|: |.|..:.....:||:.||||      |:.|:|.|  .|:...|:....|...:
  Fly   115 GQQIIFVETKNVIVHEDWIAETITNDISLIKLPVPIEFNKYIQPAK--LPVKSDSYSTYGGENAI 177

Human   187 VSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDSCQGDSGGPVVC 251
            .||||...........:||...:.:::...|...|...:..:..|.....|..:|.||||||:|.
  Fly   178 ASGWGKISDSATGATDILQYATVPIMNNSGCSPWYFGLVAASNICIKTTGGISTCNGDSGGPLVL 242

Human   252 ---NGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQE 287
               :.:|.|..|:|.........|||:|.:..:..||:|
  Fly   243 DDGSNTLIGATSFGIALGCEVGWPGVFTRITYYLDWIEE 281

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		6/33 (18%)
		Tryp_SPc	66..285	CDD:214473	66/234 (28%)
CG10472	NP_648017.1	Tryp_SPc	46..279	CDD:214473	66/234 (28%)