Protein Alignment KLK5 and Jon65Aiii

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_648013.1
• Gene: Jon65Aiii / 38683
• FlyBaseID: FBgn0035665
• Length: 274
• Species: Drosophila melanogaster
• Alignment Length: 288
• Identity: 69/288 - (23%)
• Similarity: 110/288 - (38%)
• Gaps: 41/288 - (14%)

Human    15 LITALLLGVTEHVLANNDVSCDHPSNTVPSGSNQDLGAGAGEDARSDDSSSRIINGSDCDMHTQP 79
            ::.||.|......|....|.. ||.: :|:.:|.:               .||.||........|
  Fly     5 VVFALALATASAGLLPQQVPI-HPRD-LPAVTNIE---------------GRITNGKTATSGQFP 52

Human    80 WQAALLL--RPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLSPVYESGQQMFQGVKS--- 139
            :|..|..  .....:||..::...|:||||||......|.: :|..:  ..:..|:.|.|.:
  Fly    53 YQVGLSFASTSGSWWCGGSIIDNTWVLTAAHCTSGASAVTI-YYGAT--VRTSAQLVQTVSADNF 114

Human   140 IPHPGYSHPGHSNDLMLIKLNRRIRPT--------KDVRPINVSSHCPSAGTKCLVSGWGTTKSP 196
            :.|..|:.....||:.|||     .||        |...|....::....|.:.:.||||.|...
  Fly   115 VQHASYNSIVLRNDISLIK-----TPTVAFTALINKVELPAIAGTYSTYTGQQAIASGWGKTSDS 174

Human   197 QVHFPKVLQCLNISVLSQKRCEDAYPRQI-DDTMFCAGDKAGRDSCQGDSGGP--VVCNGSLQGL 258
            .......||.....|:|..:|::.|...: .:.:.|........:|.||||||  :|.:..|.|:
  Fly   175 ATSVANTLQYEVFEVVSVSQCQNTYGSLVATNNVICVATPNKVSTCNGDSGGPLVLVSDSKLIGV 239

Human   259 VSWGDYPCARPNRPGVYTNLCKFTKWIQ 286
            .|:..........|..:|.:..:..||:
  Fly   240 TSFVSSAGCESGAPAGFTRVTSYLDWIK 267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		5/30 (17%)
		Tryp_SPc	66..285	CDD:214473	58/234 (25%)
Jon65Aiii	NP_648013.1	Tryp_SPc	39..266	CDD:214473	58/234 (25%)