Protein Alignment KLK5 and CG6462

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_648011.1
• Gene: CG6462 / 38681
• FlyBaseID: FBgn0035663
• Length: 319
• Species: Drosophila melanogaster
• Alignment Length: 247
• Identity: 70/247 - (28%)
• Similarity: 114/247 - (46%)
• Gaps: 21/247 - (8%)

Human    65 SRIINGSDCDMHTQPWQAALLLR---PNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLSPV 126
            :||..|........|:|..|:::   .:.:.||..|:..|::||||||.......::  |:.:.|
  Fly    75 TRIAGGELATRGMFPYQVGLVIQLSGADLVKCGGSLITLQFVLTAAHCLTDAIAAKI--YTGATV 137

Human   127 YESGQQMFQGVK-----SIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPS----AG 182
            :...:...:.::     .|.:|.|...|..:||.||:|.|::|.::.|:||.::.....    .|
  Fly   138 FADVEDSVEELQVTHRDFIIYPDYLGFGGYSDLALIRLPRKVRTSEQVQPIELAGEFMHQNFLVG 202

Human   183 TKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAY-PRQIDDTM-FCAGDKAGRDSCQGDS 245
            ....:||||..........::||.|:..|:.|:||...: |..:.... .|.....||.:|.|||
  Fly   203 KVVTLSGWGYLGDSTDKRTRLLQYLDAEVIDQERCICYFLPGLVSQRRHLCTDGSNGRGACNGDS 267

Human   246 GGPVVCN----GSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWI-QETIQAN 292
            |||||.:    ..|.|:.|:|.........|.|||.:..:..|| |:|...|
  Fly   268 GGPVVYHWRNVSYLIGVTSFGSAEGCEVGGPTVYTRITAYLPWIRQQTAMTN 319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		1/2 (50%)
		Tryp_SPc	66..285	CDD:214473	65/236 (28%)
CG6462	NP_648011.1	Tryp_SPc	77..314	CDD:238113	66/238 (28%)