Protein Alignment KLK5 and CG10477

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_648010.1
• Gene: CG10477 / 38679
• FlyBaseID: FBgn0035661
• Length: 272
• Species: Drosophila melanogaster
• Alignment Length: 276
• Identity: 73/276 - (26%)
• Similarity: 110/276 - (39%)
• Gaps: 34/276 - (12%)

Human    27 VLANNDVSCD--------HP--SNTVPSGSNQDLGAGAGEDARSDDSSSRIINGSDCDMHTQPWQ 81
            |||...||.|        ||  |:.|||                  ...||.||:....:..|:|
  Fly     8 VLAIATVSADILRQDTPVHPRDSSAVPS------------------IDGRITNGNKAAANQFPYQ 54

Human    82 AALLLRPN--QLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLSPVYESGQQMFQGVKSIPHPG 144
            ..|..:.:  ..:||..::...|:||||||.|....|.:.:.|........::.....|.:.|.|
  Fly    55 VGLSFKSSAGSWWCGGSIIANTWVLTAAHCTKGASSVTIYYGSTVRTSAKLKKKVSSSKFVQHAG 119

Human   145 YSHPGHSNDLMLIK---LNRRIRPTKDVRPINVSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQC 206
            |:.....||:.|||   :...:...|...|...||:...||...:.||||.|....:.....||.
  Fly   120 YNAATLRNDISLIKTPSVTFTVSINKIALPAIASSYSTYAGQTAVASGWGRTSDSSIAVATNLQY 184

Human   207 LNISVLSQKRCEDAYPRQ-IDDTMFCAGDKAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPN 270
            ....|::...|:..:... :...:.|......:.:||||||||:..|..|.|:.|:........|
  Fly   185 AQFQVITNAVCQKTFGSSVVTSGVICVESINKKSTCQGDSGGPLALNNRLIGVTSFVSSKGCEKN 249

Human   271 RPGVYTNLCKFTKWIQ 286
            .|..:|.:..:..||:
  Fly   250 APAGFTRVTSYLDWIK 265

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		7/32 (22%)
		Tryp_SPc	66..285	CDD:214473	59/224 (26%)
CG10477	NP_648010.1	Tryp_SPc	39..264	CDD:214473	59/224 (26%)