Protein Alignment KLK5 and CG1299

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_647862.1
• Gene: CG1299 / 38496
• FlyBaseID: FBgn0035501
• Length: 511
• Species: Drosophila melanogaster
• Alignment Length: 290
• Identity: 89/290 - (30%)
• Similarity: 132/290 - (45%)
• Gaps: 47/290 - (16%)

Human    38 PSNTVPSGSNQ------DLGAGAGEDARSDDSSSRIINGSDCDMHTQPWQAALLL---RPNQLYC 93
            ||..||..:::      ::..|.|...   ....:|:.|........||.|.|..   ..:...|
  Fly   229 PSQIVPKNTDEIPRRLLNVEEGCGSTV---GYFKKIVGGEVSRKGAWPWIALLGYDDPSGSPFKC 290

Human    94 GAVLVHPQWLLTAAHC-RKKVFRVRLGHYSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLI 157
            |..|:..:.:|||||| |:.:..||||.:.||...|:|.......:.:.||.|:.....:|:.::
  Fly   291 GGTLITARHVLTAAHCIRQDLQFVRLGEHDLSTDTETGHVDINIARYVSHPDYNRRNGRSDMAIL 355

Human   158 KLNRRIRPTKDVRPINVSSHCPS------AGTKCLVSGWGTT----KSPQVHFPKVLQCLNISVL 212
            .|.|.:..|..:.||.: .|..:      .|....|:|||.|    :|.|     ||..|.|.:.
  Fly   356 YLERNVEFTSKIAPICL-PHTANLRQKSYVGYMPFVAGWGKTMEGGESAQ-----VLNELQIPIY 414

Human   213 SQKRCEDAYPR--------QIDDTMFCAGD-KAGRDSCQGDSGGPVVC----NGSLQ----GLVS 260
            ..|.|..:|.:        |.|..:.|||. ..|:|:||||||||::.    .|.|:    |:||
  Fly   415 DNKVCVQSYAKEKRYFSADQFDKAVLCAGVLSGGKDTCQGDSGGPLMLPEPYQGQLRFYLIGVVS 479

Human   261 WGDYPCARPNRPGVYTNLCKFTKWIQETIQ 290
            :| ..|||||.||||::...|..||.:.:|
  Fly   480 YG-IGCARPNVPGVYSSTQYFMDWIIQQVQ 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		6/35 (17%)
		Tryp_SPc	66..285	CDD:214473	80/249 (32%)
CG1299	NP_647862.1	CLIP	37..92	CDD:463440
		CLIP	164..216	CDD:463440
		Tryp_SPc	261..503	CDD:238113	80/248 (32%)