Protein Alignment KLK5 and CG13430

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_001027441.1
• Gene: CG13430 / 3772580
• FlyBaseID: FBgn0034518
• Length: 267
• Species: Drosophila melanogaster
• Alignment Length: 254
• Identity: 85/254 - (33%)
• Similarity: 138/254 - (54%)
• Gaps: 25/254 - (9%)

Human    54 AGEDARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHC-----RKKV 113
            |.:::...:...||:.|.:..:...|.|.:|.|..... ||..::.|..:||||||     :.:.
  Fly    19 AAQNSTDVEQDGRIVGGWETHITFFPHQVSLQLGTRHA-CGGTIISPNIILTAAHCVLEYSKPQY 82

Human   114 FRVRLGHYSLSPVYESGQQMFQGVKSIPHPGYSHPGH-SNDLMLIKLNRRIRPTKDVRPINVSSH 177
            :.:|.|    |..:..|....:..|.||||.:..|.. :||:.:::|.:.:..::|:|||::::.
  Fly    83 YVIRAG----SSDWTKGGSYIRVKKIIPHPEFHDPTRMNNDIAIVQLQQPLVYSQDIRPISLATS 143

Human   178 ----CPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAY--PRQIDDTMFCAGDKA 236
                .|:|  :..|||||:|...|:...|.|:...:.:..|.:|...|  ...:.:||||||.:|
  Fly   144 KDIIMPTA--QLFVSGWGSTSISQMQPEKRLRYTVVHLRDQNQCARNYFGAGTVTNTMFCAGTQA 206

Human   237 -GRDSCQGDSGGPVV--CNGSLQ--GLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQ 290
             ||||||||||||:|  .:|.|:  |:|||| :.||....||:||.:..:..||.:||:
  Fly   207 GGRDSCQGDSGGPLVTSIDGRLKLYGIVSWG-FGCANAMFPGIYTKVSAYDDWIAQTIE 264

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		2/13 (15%)
		Tryp_SPc	66..285	CDD:214473	80/235 (34%)
CG13430	NP_001027441.1	Tryp_SPc	31..259	CDD:214473	80/235 (34%)