Protein Alignment KLK5 and CG32269

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_647788.1
• Gene: CG32269 / 3772569
• FlyBaseID: FBgn0052269
• Length: 332
• Species: Drosophila melanogaster
• Alignment Length: 329
• Identity: 104/329 - (31%)
• Similarity: 150/329 - (45%)
• Gaps: 52/329 - (15%)

Human     3 TARPPWMW-----VLCALITALLLGVTEHVLANND-----VSCDHPSNTVPSGSNQDLGAGAGED 57
            |.....:|     :|..|:.|.|..:.|.|.||..     :..|:.:..:....||   .|...:
  Fly    18 TVHSDMLWRCEYLILGMLLLAELTQLGEAVTANQQRRNRRLRSDNGTKRLTGTKNQ---TGIRSN 79

Human    58 AR--------------------SDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQW 102
            .|                    |....|||:.|:...:.|.|:  .:.||.....|...|:..||
  Fly    80 RRQGTARKLSAKRVNQNKKAATSSKIQSRIVGGTSTTISTTPY--IVQLRRGSNLCSGSLITEQW 142

Human   103 LLTAAHCRK----KVFRVRLGHYSLSPVYESGQQMFQGVKSIPH--PGYSHPGHSNDLMLIKLNR 161
            :||||||.|    ..|.||.|..:|    :....:.:.|.|| |  |.::....:.|..|:|||:
  Fly   143 VLTAAHCVKGYSASDFTVRGGTTTL----DGSDGVTRSVSSI-HVAPKFTSKKMNMDAALLKLNQ 202

Human   162 RIRPTKDVRPINVSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQ-- 224
            .:..| ::..|::.::.|.||::..::|||.||.......|.||...|.|:.|::|...|..|
  Fly   203 SLTGT-NIGTISMGNYRPKAGSRVRIAGWGVTKEGSTTASKTLQTAQIRVVRQQKCRKDYRGQAT 266

Human   225 IDDTMFCAGDKAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETI 289
            |...|.|| ..||:|||.|||||||..|.:|.|:||:| |.|||...|||||.:....:| ...|
  Fly   267 ITKYMLCA-RAAGKDSCSGDSGGPVTRNNTLLGIVSFG-YGCARAGYPGVYTAVVAIRQW-ATNI 328

Human   290 QANS 293
            .||:
  Fly   329 MANN 332

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		7/50 (14%)
		Tryp_SPc	66..285	CDD:214473	83/226 (37%)
CG32269	NP_647788.1	Tryp_SPc	108..324	CDD:214473	83/225 (37%)