Protein Alignment KLK5 and CG32270

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_728837.1
• Gene: CG32270 / 3772375
• FlyBaseID: FBgn0052270
• Length: 259
• Species: Drosophila melanogaster
• Alignment Length: 235
• Identity: 87/235 - (37%)
• Similarity: 123/235 - (52%)
• Gaps: 16/235 - (6%)

Human    64 SSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHC----RKKVFRVRLGHYSLS 124
            |.||:.|...|:..||....:..|.| ..||..||.|:.:||||||    ....|.||.|...||
  Fly    28 SPRIVGGHPSDVWHQPHMVNIRRRGN-FECGGSLVTPRCVLTAAHCLNDGNPSDFVVRGGVTYLS 91

Human   125 PVYESGQQMFQGVKSIPHP-GYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSAGTKCLVS 188
            .:..|     :.|:.|..| .||.....:|:.|::|.:.:: ....:||:::...|..|:...||
  Fly    92 DMRNS-----RYVRKILMPSAYSRTTLDHDVALLQLKQPLQ-ASIAKPISLAVRSPRPGSFVRVS 150

Human   189 GWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYP--RQIDDTMFCAGDKAGRDSCQGDSGGPVV- 250
            |||.|.|.....|..||.:::.|:.|:.|.|.|.  |.|..:||||.....:|:|.||||||||
  Fly   151 GWGLTDSSSTSLPNQLQSVHVQVMPQRECRDLYRGYRNITSSMFCASVPGLKDACAGDSGGPVVN 215

Human   251 CNGSLQGLVSWG-DYPCARPNRPGVYTNLCKFTKWIQETI 289
            .||.|.|:|||| .:.||..:.||||:::...:.||.:.|
  Fly   216 SNGILVGVVSWGRAHRCAARDSPGVYSDVSYLSDWIADNI 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		2/3 (67%)
		Tryp_SPc	66..285	CDD:214473	83/227 (37%)
CG32270	NP_728837.1	Tryp_SPc	30..251	CDD:214473	83/227 (37%)