Protein Alignment KLK5 and CG30414

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_611789.2
• Gene: CG30414 / 37705
• FlyBaseID: FBgn0050414
• Length: 305
• Species: Drosophila melanogaster
• Alignment Length: 341
• Identity: 81/341 - (23%)
• Similarity: 123/341 - (36%)
• Gaps: 115/341 - (33%)

Human    12 LCALITALLL--GVTEHVLANNDVSCDHPSNTVPSGSNQDLGAGAGEDARSDDSSSRIINGSDCD 74
            |..|:.::.|  |...|:|   |.||   ..|.|                  :....|..|:|..
  Fly     8 LALLVCSIQLGEGAPGHLL---DSSC---GTTKP------------------EFIPMITGGADAG 48

Human    75 MHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHC----------------------------RK 111
            :.:.||...:|   .:..||..|:..:::||||||                            ..
  Fly    49 LFSNPWMVKVL---GEKLCGGSLITSRFVLTAAHCIVSTHMRVRLGEYKTRFPGKDCSRCVPKSY 110

Human   112 KVFRVRLGHYS---------LSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTK 167
            |:.|:|||.|.         :...||....     :.|.|..| :....||:.|:::...::.:.
  Fly   111 KLRRIRLGEYDTRFPGKDCCVPKSYELAVD-----RKILHADY-NLNLDNDIGLLRMKSFVQYSD 169

Human   168 DVRPINVSSHCPSAGTKCL-------------VSGWGTTK--SPQVHFPKVLQCLNISVLSQKRC 217
            .||||            ||             ::|||.|.  :|.    :.||...:.......|
  Fly   170 YVRPI------------CLLVEGHMAESPIFNITGWGVTNDGTPS----RRLQRATVYNTDLHFC 218

Human   218 EDAYPRQIDDTMFCAGDKAGRDSCQGDSGGPVVCN----GS----LQGLVSWGDYPCARPNRPGV 274
            ...:.:|:|::..||.. ...|:|.||||||:...    ||    ..||||:|...|   :...|
  Fly   219 RSKFTKQVDESQICAAG-TNSDACHGDSGGPLSAQVPFAGSWLTFQYGLVSYGSAAC---HSFSV 279

Human   275 YTNLCKFTKWIQETIQ 290
            |||:.....||...|:
  Fly   280 YTNVTHHRDWIVNAIE 295

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		2/30 (7%)
		Tryp_SPc	66..285	CDD:214473	67/278 (24%)
CG30414	NP_611789.2	Tryp_SPc	41..290	CDD:238113	67/277 (24%)