Protein Alignment KLK5 and CG3700

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_611736.1
• Gene: CG3700 / 37640
• FlyBaseID: FBgn0034796
• Length: 360
• Species: Drosophila melanogaster
• Alignment Length: 315
• Identity: 91/315 - (28%)
• Similarity: 136/315 - (43%)
• Gaps: 66/315 - (20%)

Human    31 NDVSC-----DHPSNTVPSGSNQDLGAGAGE--DARSD-DSSSRIINGSDCDMHTQPWQAAL-LL 86
            ||:.|     || .|..|:...:.......:  :.||. .|:..|:.|:.......|:.|.: ..
  Fly    59 NDIVCCPIPLDH-QNLKPAEQTRPFEKQCKQYNEVRSACQSTPFIVGGTKASGKEFPFMALIGTH 122

Human    87 RPNQLY------CGAVLVHPQWLLTAAHCRK---------------KVFRVRLGHYSLSPVYESG 130
            |||:..      ||..:|||:::||||||.:               ..|.||||....:...:..
  Fly   123 RPNKSKSDINWDCGGSVVHPKFVLTAAHCLETDESKAERLDPNFDSPKFVVRLGELDYNSTTDDA 187

Human   131 -QQMFQGVKSIPHPGY----SHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHC--PSAGT---KC 185
             .|.|:.|..:.||||    ...|..||:.|::|:|:.....     :|::.|  |.:|.   :.
  Fly   188 LVQDFRVVNYVVHPGYDTEDEEQGFKNDIALVELDRKAEFND-----HVAAVCLPPDSGNDVQQV 247

Human   186 LVSGWGTT----KSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDD-TMFCAGDKAGR-DSCQGD 244
            ..:|||.|    ||.  |..||    |:...|.:.|:......||. |.||||..:.: |:|.||
  Fly   248 TAAGWGFTADGVKSS--HLLKV----NLQRFSDEVCQKRLRFSIDTRTQFCAGSMSSQADTCNGD 306

Human   245 SGGPVV-------CNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQAN 292
            ||||:.       |...:.|:||:| ..|.....|.|||.:..:|.||:..:..|
  Fly   307 SGGPIFVQHPLYPCLKQVIGIVSYG-LVCGSQGLPSVYTKVHLYTDWIESIVWGN 360

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		6/33 (18%)
		Tryp_SPc	66..285	CDD:214473	78/263 (30%)
CG3700	NP_611736.1	Tryp_SPc	102..356	CDD:238113	80/265 (30%)