Protein Alignment KLK5 and CG9294

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_995920.1
• Gene: CG9294 / 37491
• FlyBaseID: FBgn0034666
• Length: 352
• Species: Drosophila melanogaster
• Alignment Length: 341
• Identity: 95/341 - (27%)
• Similarity: 147/341 - (43%)
• Gaps: 76/341 - (22%)

Human    10 WVLCALITALLLGVTEHVLANND-------VSCDHPSNTVPSGSNQDLGAGAGEDARSDDSSS-- 65
            |:|.||...|..|.||..:..|:       .|...||.|..: |...:...:....|:..:||
  Fly     5 WILIALFCGLCSGSTERRIRPNEGKIFEWLGSILLPSTTTTT-STPVVATTSTTTRRTTTTSSTT 68

Human    66 -------------------------------RIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVH 99
                                           :|:.|.:..:|..||.|.:|:. |:.||...|::
  Fly    69 SRTTTSRTTVANFPIERDCVTCRCGLINTLYKIVGGQETRVHQYPWMAVILIY-NRFYCSGSLIN 132

Human   100 PQWLLTAAHCRK----KVFRVRLGHYSLSPVYES--GQQMFQGVKSIPHPGYSHPGHSNDLMLIK 158
            ..::||||||.:    ::..:|...::.|...:.  .|:....||  .|..|:.....|||.:::
  Fly   133 DLYVLTAAHCVEGVPPELITLRFLEHNRSHSNDDIVIQRYVSRVK--VHELYNPRSFDNDLAVLR 195

Human   159 LNR-------RIRPTKDVRPINVSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKR 216
            ||:       |:||.  ..|:...|.....|   :|:|||..:..... ...|:.:::.||.|..
  Fly   196 LNQPLDMRHHRLRPI--CLPVQSYSFDHELG---IVAGWGAQREGGFG-TDTLREVDVVVLPQSE 254

Human   217 CEDA---YPRQIDDTMFCAG--DKAGRDSCQGDSGGPVVCN-----GSLQ--GLVSWGDYPCARP 269
            |.:.   .|.||.|.|.|||  .:.|:|:|.||||||:...     |..|  |:|||| ..||||
  Fly   255 CRNGTTYRPGQITDNMMCAGYISEGGKDACSGDSGGPLQTTFDEQPGQYQLAGIVSWG-VGCARP 318

Human   270 NRPGVYTNLCKFTKWI 285
            ..|||||.:.::.:|:
  Fly   319 QSPGVYTRVNQYLRWL 334

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		7/63 (11%)
		Tryp_SPc	66..285	CDD:214473	77/243 (32%)
CG9294	NP_995920.1	Tryp_SPc	101..334	CDD:238113	77/242 (32%)