Protein Alignment KLK5 and CG30283

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_611587.2
• Gene: CG30283 / 37454
• FlyBaseID: FBgn0260477
• Length: 273
• Species: Drosophila melanogaster
• Alignment Length: 299
• Identity: 79/299 - (26%)
• Similarity: 130/299 - (43%)
• Gaps: 60/299 - (20%)

Human    11 VLCALITALLLGVTEHVLANNDVSCDHPSNTVPSGSNQDLGAGAGEDARSDDSSSRIINGSDCDM 75
            ||.|..:.::||      :.:....:||..|||.                  |..:|:.|.:..:
  Fly    11 VLLAASSVVVLG------SESGSFLEHPCGTVPI------------------SQFKILGGHNAPV 51

Human    76 HTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHC-RKKVFRVRLGHYSLSPVYESGQQMFQGVKS 139
            .:.||. |:::.....:||..|:..:::||:||| .....:||||...    .|:..|.|.....
  Fly    52 ASAPWM-AMVMGEGGFHCGGTLITNRFVLTSAHCIANGELKVRLGVLE----REAEAQKFAVDAM 111

Human   140 IPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPI---------NVSSHCPSAGTKCLVSGWGTTKS 195
            ..|..|....|  ||.|::|.:|:..:.::.||         |:..|.    .|....|||.|:|
  Fly   112 FVHTDYYFDQH--DLALLRLAKRVHYSDNISPICLLLDPLVKNIDEHI----VKFRTYGWGKTES 170

Human   196 PQVHFPKVLQCLNISVLSQKRCEDAYP-RQIDDTMFCAGDKAGRDSCQGDSGGP---VVCNGSLQ 256
            ..  ..::||..::..|.:..|...|| :||:....|| :.|..::|.||||||   :|....:|
  Fly   171 RS--SSRMLQKTSLFNLHRSECAKQYPHQQINRNHICA-ESANANTCNGDSGGPLTAIVTYDHVQ 232

Human   257 -----GLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQ 290
                 |:.|:|...|::..   |:||:.....||..|::
  Fly   233 MVFQFGVTSFGHADCSKAT---VFTNVMTHLDWIVNTVR 268

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		6/30 (20%)
		Tryp_SPc	66..285	CDD:214473	65/237 (27%)
CG30283	NP_611587.2	Tryp_SPc	42..263	CDD:214473	65/237 (27%)