Protein Alignment KLK5 and CG11192

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_611479.2
• Gene: CG11192 / 37309
• FlyBaseID: FBgn0034507
• Length: 279
• Species: Drosophila melanogaster
• Alignment Length: 268
• Identity: 91/268 - (33%)
• Similarity: 134/268 - (50%)
• Gaps: 41/268 - (15%)

Human    50 LGAGAGEDARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHC----- 109
            |.|.||  |.......||:.|....:...|:|.::.|:...: ||..::....:||||||
  Fly    13 LVAYAG--ATPTPGDGRIVGGEVATIQEFPYQVSVQLQGRHI-CGGAIIGIDTVLTAAHCFEDPW 74

Human   110 RKKVFRVRLGHYSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINV 174
            ....:.||:|    |..:|||..:....:.|.|..|:...|.|||.|:.||.::..|:.::|:.:
  Fly    75 SSADYTVRVG----SSEHESGGHVLSLRRVIAHGDYNPQSHDNDLALLILNGQLNFTEHLQPVPL 135

Human   175 SSHC--PSAGTKCLVSGWG-----------TTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQID 226
            ::..  |:|.|:..|||||           ...|||:.|      :::.::...:|..||.:.:.
  Fly   136 AALADPPTADTRLQVSGWGFQAEESAVSGEVGVSPQLRF------VDVDLVESNQCRRAYSQVLP 194

Human   227 DT--MFCAGDKAGRDSCQGDSGGPVVCNGS------LQGLVSWGDYPCARPNRPGVYTNLCKFTK 283
            .|  |.||. :.||||||||||||:|...:      |.|:|||| ..||.||.||||||:..|..
  Fly   195 ITRRMICAA-RPGRDSCQGDSGGPLVGYAAEEGPARLYGIVSWG-LGCANPNFPGVYTNVAAFRS 257

Human   284 WIQETIQA 291
            ||.|.:.|
  Fly   258 WIDEQLDA 265

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		6/17 (35%)
		Tryp_SPc	66..285	CDD:214473	82/244 (34%)
CG11192	NP_611479.2	Tryp_SPc	27..259	CDD:214473	82/244 (34%)