Protein Alignment KLK5 and CG4927

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_001033953.1
• Gene: CG4927 / 36852
• FlyBaseID: FBgn0034139
• Length: 362
• Species: Drosophila melanogaster
• Alignment Length: 307
• Identity: 79/307 - (25%)
• Similarity: 127/307 - (41%)
• Gaps: 50/307 - (16%)

Human    29 ANNDVSCDHPSNTVPSGSNQDLGAGAG------------EDARSDDSSSRIINGSDCDMHTQPWQ 81
            :|:.|.|..|:|..|  .:|...|..|            |...|..::..|:.|:.......|:.
  Fly    57 SNHIVCCLLPNNMQP--QSQQFSANIGLRRFEKECRRFNEIRTSCRTTPFIVGGAKAAGREFPFM 119

Human    82 AALLLR---PNQL--YCGAVLVHPQWLLTAAHCRK---------------KVFRVRLGHYSLSPV 126
            |.|..|   .:|:  .|||:::||:::||||||.:               ..:.||||....:..
  Fly   120 ALLGQRGKNSSQIDWDCGAIIIHPKFVLTAAHCLETSETKEQRLDPNYDGPKYVVRLGELDYNST 184

Human   127 YESGQ-QMFQGVKSIPHPGYSHP----GHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSAGTKCL 186
            .:..| |.|:.:..:.||.|...    ...||:.:::|......::.|.|..:.....:...:..
  Fly   185 TDDAQPQDFRVLNYVVHPAYGEDDDTGSRKNDIAVVELEMEATFSEYVAPACLPLDGGNEQLQVA 249

Human   187 VSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQID-DTMFCAGDKA-GRDSCQGDSGGPV 249
            .:|||.| |...|....|..:::.......|......:|| .|..|||.:: ..|:|.|||||||
  Fly   250 AAGWGAT-SESGHASSHLLKVSLDRYDVAECSQRLEHKIDVRTQLCAGSRSTSADTCYGDSGGPV 313

Human   250 V-------CNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETI 289
            .       |...:.|:.|:| ..|.....|.|||.:..:|.||:..:
  Fly   314 FVQHPIYSCLKQVIGITSYG-LVCGVQGLPSVYTKVHLYTDWIENIV 359

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		8/42 (19%)
		Tryp_SPc	66..285	CDD:214473	66/252 (26%)
CG4927	NP_001033953.1	Tryp_SPc	105..358	CDD:238113	68/254 (27%)