Protein Alignment KLK5 and CG8299

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_611066.1
• Gene: CG8299 / 36751
• FlyBaseID: FBgn0034052
• Length: 260
• Species: Drosophila melanogaster
• Alignment Length: 238
• Identity: 79/238 - (33%)
• Similarity: 124/238 - (52%)
• Gaps: 14/238 - (5%)

Human    64 SSRIINGSDCDMHTQPWQAALLLRPNQL--YCGAVLVHPQWLLTAAHCRK----KVFRVRLGHYS 122
            |:.|:.|...|:...|:|.::.|....|  .||..:..|:.::|||||.|    ...|:..|..|
  Fly    25 STHIVGGDQADIADFPYQVSVRLETYMLLHICGGSIYAPRVVITAAHCIKGRYASYIRIVAGQNS 89

Human   123 LSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSAGTKCLV 187
            ::.:.|.|.::   .|.|||.||:...:.||:.||.....:..:..|:||.|:...|.:|.:.:|
  Fly    90 IADLEEQGVKV---SKLIPHAGYNKKTYVNDIGLIITREPLEYSALVQPIAVALEAPPSGAQAVV 151

Human   188 SGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQ---IDDTMFCAGD-KAGRDSCQGDSGGP 248
            ||||.........|.:|:.:.:.::.:..|...|..:   :.|.|.|||. :.|:|:|.||||||
  Fly   152 SGWGKRAEDDEALPAMLRAVELQIIEKSTCGAQYLTKDYTVTDEMLCAGYLEGGKDTCNGDSGGP 216

Human   249 VVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQA 291
            :..:|.|.|:|||| ..|.|...|||||::.....||:|..:|
  Fly   217 LAVDGVLVGVVSWG-VGCGREGFPGVYTSVNSHIDWIEEQAEA 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		1/3 (33%)
		Tryp_SPc	66..285	CDD:214473	74/228 (32%)
CG8299	NP_611066.1	Tryp_SPc	27..252	CDD:214473	74/228 (32%)