Protein Alignment KLK5 and Ser8

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_610874.1
• Gene: Ser8 / 36489
• FlyBaseID: FBgn0019928
• Length: 260
• Species: Drosophila melanogaster
• Alignment Length: 301
• Identity: 84/301 - (27%)
• Similarity: 135/301 - (44%)
• Gaps: 61/301 - (20%)

Human     9 MWVLCALITALLLGVTEHVLANNDVSCDHPSNTVPSGSNQDLGAGAGEDARSDDSSSRIINGSDC 73
            |.:|.|...|||      .|.|..|        :|          .|.:.::.....||:.|:..
  Fly     1 MSLLIATFLALL------ALTNGAV--------IP----------IGLEPQTSSLGGRIVGGTAS 41

Human    74 DMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHC-----RKKVFRVRLGHYSLSPVYESGQQM 133
            .:..:|||.: |.|....:||..::....::|||||     .....|:|.|         |.::.
  Fly    42 SIEDRPWQVS-LQRSGSHFCGGSIISNNIIVTAAHCLDTPTTVSNLRIRAG---------SNKRT 96

Human   134 FQGV-------KSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSAGTKCLVSGWG 191
            :.||       |:  |..|:.....||:.:::|..::.....::.|.::|..|:.|:...:||||
  Fly    97 YGGVLVEVAAIKA--HEAYNSNSKINDIGVVRLKTKLTFGSTIKAITMASATPAHGSAASISGWG 159

Human   192 --TTKSPQVHFPKVLQCLNISVLSQKRCEDA---YPRQIDDTMFCAGDKAGRDSCQGDSGGPVVC 251
              :|..|.   ...|..::..::.:.:|..:   |...|..||.||. ...:|:||||||||:|.
  Fly   160 KTSTDGPS---SATLLFVDTRIVGRSQCGSSTYGYGSFIKATMICAA-ATNKDACQGDSGGPLVS 220

Human   252 NGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWI---QETI 289
            .|.|.|:|||| ..||..|.||||.|:.:...|:   |:|:
  Fly   221 GGQLVGVVSWG-RDCAVANYPGVYANIAELRDWVLQAQKTV 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		3/30 (10%)
		Tryp_SPc	66..285	CDD:214473	70/235 (30%)
Ser8	NP_610874.1	Tryp_SPc	35..253	CDD:238113	69/234 (29%)