Protein Alignment KLK5 and iotaTry

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_523695.1
• Gene: iotaTry / 36223
• FlyBaseID: FBgn0015001
• Length: 252
• Species: Drosophila melanogaster
• Alignment Length: 249
• Identity: 73/249 - (29%)
• Similarity: 114/249 - (45%)
• Gaps: 29/249 - (11%)

Human    57 DARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKK----VFRVR 117
            ||...:::.|||.|||..:...|||.::.:.... .||.|:...:.::||.||..:    :.:||
  Fly    18 DASDVEATGRIIGGSDQLIRNAPWQVSIQISARH-ECGGVIYSKEIIITAGHCLHERSVTLMKVR 81

Human   118 LGHYSLSPVYESGQQMFQGVKSIPHPGYS-HPGHSN-----DLMLIKLNRRIRPTKDVRPINVSS 176
            :|          .|....|...:|...|. |....:     |:.:::|:..:......|.||::|
  Fly    82 VG----------AQNHNYGGTLVPVAAYKVHEQFDSRFLHYDIAVLRLSTPLTFGLSTRAINLAS 136

Human   177 HCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCED---AYPRQ-IDDTMFCAGDKAG 237
            ..||.||...|:|||.|.:..:  ...||...:.::.:..|..   .|... :.:...||. ...
  Fly   137 TSPSGGTTVTVTGWGHTDNGAL--SDSLQKAQLQIIDRGECASQKFGYGADFVGEETICAA-STD 198

Human   238 RDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQA 291
            .|:|.||||||:|.:..|.|:|||| |.||..|.||||.::.....||.:...|
  Fly   199 ADACTGDSGGPLVASSQLVGIVSWG-YRCADDNYPGVYADVAILRPWIVKAANA 251

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		3/10 (30%)
		Tryp_SPc	66..285	CDD:214473	68/232 (29%)
iotaTry	NP_523695.1	Tryp_SPc	27..245	CDD:214473	68/232 (29%)