Protein Alignment KLK5 and etaTry

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_523692.1
• Gene: etaTry / 36217
• FlyBaseID: FBgn0011554
• Length: 262
• Species: Drosophila melanogaster
• Alignment Length: 247
• Identity: 80/247 - (32%)
• Similarity: 122/247 - (49%)
• Gaps: 30/247 - (12%)

Human    58 ARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQ-----LYCGAVLVHPQWLLTAAHC----RKKV 113
            |.|..|..||:.|:|...:...:...|..|.:.     ..||..::....:.|||||    ..:.
  Fly    19 AVSAQSDGRIVGGADTSSYYTKYVVQLRRRSSSSSSYAQTCGGCILDAVTIATAAHCVYNREAEN 83

Human   114 FRVRLGHYSLSPVYESGQQMFQGV-----KSIPHPGYSHPGHSNDLMLIKLNRRIRPT---KDVR 170
            |.|..|        :..:....||     |.|||..|:.....||:.|:.::..: |.   ..:.
  Fly    84 FLVVAG--------DDSRGGMNGVVVRVSKLIPHELYNSSTMDNDIALVVVDPPL-PLDSFSTME 139

Human   171 PINVSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYP-RQIDDTMFCAG- 233
            .|.::|..|:.|.:..:||||.||...:...: ||.:.:.::..::|::||. |.|.:.|.|||
  Fly   140 AIEIASEQPAVGVQATISGWGYTKENGLSSDQ-LQQVKVPIVDSEKCQEAYYWRPISEGMLCAGL 203

Human   234 DKAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWI 285
            .:.|:|:||||||||:|....|.|:||||: .|||||.||||.|:..:..||
  Fly   204 SEGGKDACQGDSGGPLVVANKLAGIVSWGE-GCARPNYPGVYANVAYYKDWI 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		4/9 (44%)
		Tryp_SPc	66..285	CDD:214473	75/237 (32%)
etaTry	NP_523692.1	Tryp_SPc	27..254	CDD:214473	75/237 (32%)