Protein Alignment KLK5 and zetaTry

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_523691.1
• Gene: zetaTry / 36216
• FlyBaseID: FBgn0011556
• Length: 280
• Species: Drosophila melanogaster
• Alignment Length: 304
• Identity: 87/304 - (28%)
• Similarity: 140/304 - (46%)
• Gaps: 53/304 - (17%)

Human     8 WMWVLCALITALLLGVTEHVLANNDVSCDHPSNTVPSGSNQDLGAGAGEDARSDDSSSRIINGSD 72
            |:..|.|.:.: |:.:|:.:....|:.    ..:||.|                    ||:.|..
  Fly     5 WIVGLLAFLVS-LVALTQGLPLLEDLD----EKSVPDG--------------------RIVGGYA 44

Human    73 CDMHTQPWQAALLLR-------PNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSL--SPVYE 128
            .|:...|:|.:|..:       |.:..||..:.:...::|||||   |.......|.:  ...::
  Fly    45 TDIAQVPYQISLRYKGITTPENPFRHRCGGSIFNETTIVTAAHC---VIGTVASQYKVVAGTNFQ 106

Human   129 SGQQ-MFQGVKSI-PHPG-YSHPGHSNDLMLIKLNRRIRPTKD--VRPINVSSHCPSAGTKCLVS 188
            :|.. :...||.| .|.| ||...::||:.::.::..: |..:  ::.|.::...|..||...||
  Fly   107 TGSDGVITNVKEIVMHEGYYSGAAYNNDIAILFVDPPL-PLNNFTIKAIKLALEQPIEGTVSKVS 170

Human   189 GWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDT------MFCAGDK--AGRDSCQGDS 245
            ||||| ||..:....|..:::.::|.:.|:..|....|:|      |.|||.:  .|.|:|||||
  Fly   171 GWGTT-SPGGYSSNQLLAVDVPIVSNELCDQDYEDFGDETYRITSAMLCAGKRGVGGADACQGDS 234

Human   246 GGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETI 289
            |||:.....|.|:||||: .||.||.||||.|:.....||...:
  Fly   235 GGPLAVRDELYGVVSWGN-SCALPNYPGVYANVAYLRPWIDAVL 277

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		4/30 (13%)
		Tryp_SPc	66..285	CDD:214473	76/240 (32%)
zetaTry	NP_523691.1	Tryp_SPc	38..273	CDD:214473	76/240 (32%)