Protein Alignment KLK5 and kappaTry

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_610674.5
• Gene: kappaTry / 36215
• FlyBaseID: FBgn0043471
• Length: 263
• Species: Drosophila melanogaster
• Alignment Length: 259
• Identity: 82/259 - (31%)
• Similarity: 118/259 - (45%)
• Gaps: 45/259 - (17%)

Human    60 SDDSSSRIINGSDCDMHTQPWQAALLLRPN--QLY---CGAVLVHPQWLLTAAHCRKKVFRVRLG 119
            |.....|||||:..|:...|:..:|..|.:  ..|   |..|::..|.|:|:|.|.
  Fly    19 SGQPEGRIINGTTVDIARHPYLVSLRYRRDNESSYMHECAGVIISEQALITSAQCL--------- 74

Human   120 HYSLSP----VYESGQQMFQGVKSI--------PHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPI 172
             |.|..    |..:|.....|....        .||.|......||:.::.|:    .|.|:..:
  Fly    75 -YGLPEETKLVAVAGANTRNGTDGFIYPVANWTHHPNYDPVTVDNDIGVLLLD----TTLDLTLL 134

Human   173 NVSS-----HCPSAGTKCLVSGWGTTK--SPQVHFPKVLQCLNISVLSQKRCEDAY-PRQIDDTM 229
            .:||     ..|:.|....|:|||..:  .|..:   .|:...:.|:|.::|...| ..::.:.|
  Fly   135 GISSIGIRPERPAVGRLATVAGWGYREEWGPSSY---KLEQTEVPVVSSEQCTQIYGAGEVTERM 196

Human   230 FCAG--DKAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQA 291
            .|||  .:.|.|:||||:|||:|.:|.|.|||||| ..|||||.|.||..:..|..||:|||.|
  Fly   197 ICAGFVVQGGSDACQGDTGGPLVIDGQLVGLVSWG-RGCARPNYPTVYCYVASFVDWIEETIAA 259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		2/7 (29%)
		Tryp_SPc	66..285	CDD:214473	75/245 (31%)
kappaTry	NP_610674.5	Tryp_SPc	26..256	CDD:238113	76/247 (31%)