Protein Alignment KLK5 and lambdaTry

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_610673.1
• Gene: lambdaTry / 36214
• FlyBaseID: FBgn0043470
• Length: 272
• Species: Drosophila melanogaster
• Alignment Length: 335
• Identity: 57/335 - (17%)
• Similarity: 99/335 - (29%)
• Gaps: 114/335 - (34%)

Human    50 PEKKKVDQLNAAHYSTGKVSASFTSTAMVPE------TTHEAAVIDEDVLRYQFV--------KK 100
            ||:..:|:....::.|....:..|..|...|      |..|....||.....|:.        |.
  Fly    12 PEEAAIDKAVTENHVTQPNVSEVTRDAAARELPAFFYTAMEQVARDEGFTTGQYTIDTEDGSSKG 76

Human   101 KGYV----RLHTNKGDLNLELHCDLTP---------KTCENF----------------------- 129
            .|::    |.:..:||......|.:.|         :|.|.|
  Fly    77 DGFIGELFRAYLTEGDRREAYLCKIPPLNEARRQQFETMEIFEREVLMYNKLLPLMFAYQEAKGV 141

Human   130 --------IKLCKKQYYDGTIFHRSIRNFVIQGGDPTGTGTGGESFWGKPFKDEFRPNLSHTGRG 186
                    |..|...:|||    :|....::.                    ::.|  |:|
  Fly   142 SREDGFFSIPKCYHAHYDG----QSAEAIIVM--------------------EDLR--LNH---- 176

Human   187 VLSMANSGPNTNKSQFFITFRSCAYLDKKHTIFGRVVGG----FDTLTAMENVESDPKTDRPKEE 247
             .||.|.....:.....:|...   |.:.|.:...:...    |:....:::::.....:.|...
  Fly   177 -YSMFNKDKPVDYEHARLTMEQ---LGRYHAVSLAMKHDRPEQFEQFKMLDSMKESMSPEHPFIV 237

Human   248 VLICTTTVFVDPYEEADAQIAQERKKTQH-------QVDPEAKVKMSQPQPG--------NQGPQ 297
            :|..||.   |..|..:...|:||.|.|.       .||..|..::::|...        |....
  Fly   238 MLQKTTR---DAMETLEPHEARERNKMQKLLNGMLADVDRYANFELAEPYAVLGHGDCWINNMMY 299

Human   298 TYRQGVGKYI 307
            .|:.|..::|
  Fly   300 RYKNGTPEHI 309

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		4/17 (24%)
		Tryp_SPc	66..285	CDD:214473	48/287 (17%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	41/259 (16%)