Protein Alignment KLK5 and CG12133

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_610540.2
• Gene: CG12133 / 36036
• FlyBaseID: FBgn0033469
• Length: 340
• Species: Drosophila melanogaster
• Alignment Length: 271
• Identity: 76/271 - (28%)
• Similarity: 118/271 - (43%)
• Gaps: 53/271 - (19%)

Human    64 SSRIINGSDCDMHTQPWQAAL-------LLRPNQLYCGAVLVHPQWLLTAAHCRK----KVFRVR 117
            ||.|:.|.:...:..||...|       ..||:.: |...|:..:::||||||..    .|.|||
  Fly    59 SSYIVGGMEAQSNQFPWTVLLGYEAYTAKQRPSPM-CAGSLIASRYVLTAAHCLNVNDFYVARVR 122

Human   118 LGHYSL--SPVY---ESGQQMFQGVK-------SIPHPGY--SHPGHSNDLMLIKLNRRIRPTKD 168
            ||.:..  .|.|   .:|.:::....       .:||..|  .:..|.||:.|::|..|::.|..
  Fly   123 LGEHDTENDPDYTWLPNGAKIWAPAHVDIDVDLRVPHEQYYTRNGRHYNDIALLRLKSRVKYTLQ 187

Human   169 VRPINVSSHCPSAGTKC----------LVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPR 223
            :|||     |...|.:.          .::|||.:...|.  ..||:...||.:|...|.:.||.
  Fly   188 IRPI-----CIWPGIELSTSSFKNFPFQIAGWGDSGLQQK--STVLRQGTISGMSPDECLNRYPT 245

Human   224 QI--DDTMFCAGDKAGRDSCQGDSGGPVVCN---GS-----LQGLVSWGDYPCARPNRPGVYTNL 278
            .:  .|...||....|.|:..||||.|::.:   |:     |.|:.|:|..|.:....|.|||..
  Fly   246 LLVDKDIQICAMGWDGTDTGLGDSGSPLMASVGRGADQFYYLAGITSYGGGPSSYGYGPAVYTKT 310

Human   279 CKFTKWIQETI 289
            ..:.:||::.|
  Fly   311 SSYYEWIKKKI 321

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		2/3 (67%)
		Tryp_SPc	66..285	CDD:214473	71/263 (27%)
CG12133	NP_610540.2	Tryp_SPc	62..317	CDD:214473	71/262 (27%)