Protein Alignment KLK5 and CG1773

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_610512.1
• Gene: CG1773 / 35999
• FlyBaseID: FBgn0033439
• Length: 317
• Species: Drosophila melanogaster
• Alignment Length: 337
• Identity: 86/337 - (25%)
• Similarity: 130/337 - (38%)
• Gaps: 109/337 - (32%)

Human    16 ITALLLGV----------------TEH-VLANNDVS---CDHPSNTVPSGSNQDLGAGAGEDARS 60
            ||||:.|:                |.| :||...::   |...||.:|:   |.|
  Fly     7 ITALIWGILCLSCPPSSQAGREDWTPHELLAYEQLTQQDCGVLSNLIPA---QRL---------- 58

Human    61 DDSSSRIINGSDCDMHTQPWQAALLLRPN--QLYCGAVLVHPQWLLTAAHC-----RKKVFRVRL 118
               ..||..|....:.:|||.|.|.:..:  ...||..|:...::||||||     |.|..||.|
  Fly    59 ---RRRITGGRKSSLLSQPWMAFLHISGDIEMCRCGGSLLSELFVLTAAHCFKMCPRSKEIRVWL 120

Human   119 GHYSLSPVYESGQQMFQGVKSIP------------------HPGYSHPGHSNDLMLIKLNRRIRP 165
            |...:|...:.....:|.|.::|                  :|||       |:.|||||:::..
  Fly   121 GELDISSTSDCVTYNYQRVCALPVEEFTIDKWILHEEFNLFYPGY-------DIALIKLNKKVVF 178

Human   166 TKDVRPI------NVSSHCPSAGTKCLVSGWGTTKS-------PQVHFPKVLQCLNISVLSQKRC 217
            ...:|||      .:.:.....|...:..|||.|:|       .:||            ::.::|
  Fly   179 KDHIRPICLPLTDELLAFTLQLGQSYMAVGWGRTESRRFANSTMEVH------------INTEKC 231

Human   218 EDAYPRQIDDTMFCA-GDKAGRDSCQGDSGGPVVCNGSL--------QGLVSWGDYPCARPNRPG 273
            .|..    |.:..|| ||..  |:|.||||||::...:|        .|:||.|...|. ..:..
  Fly   232 TDGR----DTSFLCANGDYV--DTCTGDSGGPLIWKTTLFGKARTVQFGVVSTGSQNCG-AGQKA 289

Human   274 VYTNLCKFTKWI 285
            .|.::..:..||
  Fly   290 YYMDVPTYVPWI 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		6/30 (20%)
		Tryp_SPc	66..285	CDD:214473	69/265 (26%)
CG1773	NP_610512.1	Tryp_SPc	61..301	CDD:214473	69/265 (26%)