Protein Alignment KLK5 and CG8170

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_610441.2
• Gene: CG8170 / 35908
• FlyBaseID: FBgn0033365
• Length: 855
• Species: Drosophila melanogaster
• Alignment Length: 327
• Identity: 86/327 - (26%)
• Similarity: 131/327 - (40%)
• Gaps: 69/327 - (21%)

Human    13 CALITALLLGVTEHVLANNDVSCDHPSNTVPSGSNQDLG-------------------AGAGEDA 58
            |.|...|:.|..:.:|..   .|...:.:...||:..:|                   ...|...
  Fly   542 CWLSGGLIQGTCDGLLRG---CCHRTAKSANLGSSDFVGNAVDLTDLPQKNYGPVNNEPSCGISL 603

Human    59 RSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHC----RKKVFRVRLG 119
            ....:..||:.|.|....:.||||  .:|.....||..|:..:.::||.||    ..:...|.||
  Fly   604 AKQTAQRRIVGGDDAGFGSFPWQA--YIRIGSSRCGGSLISRRHVVTAGHCVARATPRQVHVTLG 666

Human   120 HYSLSPVYESGQQMFQGVKSIP-HPGYSHPGHSN--DLMLIKLNRRIRPTKDVRPINVSSHCPSA 181
            .|.::...|.......||:.|. ||.:.....::  |:.::.|.|.:.....:.||
  Fly   667 DYVINSAVEPLPAYTFGVRRIDVHPYFKFTPQADRFDISVLTLERTVHFMPHIAPI--------- 722

Human   182 GTKCL-------------VSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQ------IDD 227
               ||             .:|||.........||.||.:::.|:..:.|| .:.||      |..
  Fly   723 ---CLPEKNEDFLGKFGWAAGWGALNPGSRLRPKTLQAVDVPVIENRICE-RWHRQNGINVVIYQ 783

Human   228 TMFCAGDK-AGRDSCQGDSGGPVV--CNGS--LQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQE 287
            .|.|||.: .|:||||||||||::  .||.  |.|:||.| |.||...:||:|.::.|...|:..
  Fly   784 EMLCAGYRNGGKDSCQGDSGGPLMHDKNGRWYLIGVVSAG-YSCASRGQPGIYHSVSKTVDWVSY 847

Human   288 TI 289
            .:
  Fly   848 VV 849

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		5/49 (10%)
		Tryp_SPc	66..285	CDD:214473	75/249 (30%)
CG8170	NP_610441.2	Tryp_SPc	612..846	CDD:238113	75/249 (30%)