Protein Alignment KLK5 and CG8172

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_001097235.2
• Gene: CG8172 / 35905
• FlyBaseID: FBgn0033362
• Length: 561
• Species: Drosophila melanogaster
• Alignment Length: 332
• Identity: 105/332 - (31%)
• Similarity: 154/332 - (46%)
• Gaps: 69/332 - (20%)

Human    22 GVTEHVLANNDVSCDHPSNT---------VPS------GSNQDLGAG-AGEDARSDDS------- 63
            |:|.|:.:..|.....|.::         :|:      |:..||.|| |.::.:|..|
  Fly   235 GITNHLDSFFDAESQAPLDSAGAPPPHEPLPNAQAFAVGNVLDLNAGEAADEYQSGGSGGYHDAS 299

Human    64 -------------SSRIINGSDCDMHTQPWQAALL---LRPNQLYCGAVLVHPQWLLTAAHCRKK 112
                         |:||:.|......:.|||.||:   ....:|.||..|:..:|::|||||...
  Fly   300 YRPVPGCGEVYTRSNRIVGGHSTGFGSHPWQVALIKSGFLTRKLSCGGALISNRWVITAAHCVAS 364

Human   113 V----FRVRLGHYSLSPVYESGQQMFQGV--KSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRP 171
            .    .::|||.:.:....|.......|:  |.: ||.|:.....||:.||:|:|.:...:.:.|
  Fly   365 TPNSNMKIRLGEWDVRGQEERLNHEEYGIERKEV-HPHYNPADFVNDVALIRLDRNVVYKQHIIP 428

Human   172 INVSSHC--PS----AGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAY-----PRQI 225
            :     |  ||    .|....|:|||.|:..|...|.|||.:::.|:|..||:..:     ...|
  Fly   429 V-----CLPPSTTKLTGKMATVAGWGRTRHGQSTVPSVLQEVDVEVISNDRCQRWFRAAGRREAI 488

Human   226 DDTMFCAGDK-AGRDSCQGDSGGPVVC----NGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWI 285
            .|...|||.| .||||||||||||:..    ..:|.|||||| ..|.|.:.||||||:.:|..||
  Fly   489 HDVFLCAGYKDGGRDSCQGDSGGPLTLTMDGRKTLIGLVSWG-IGCGREHLPGVYTNIQRFVPWI 552

Human   286 QETIQAN 292
            .: :.||
  Fly   553 NK-VMAN 558

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		12/66 (18%)
		Tryp_SPc	66..285	CDD:214473	86/243 (35%)
CG8172	NP_001097235.2	Tryp_SPc	316..555	CDD:238113	87/246 (35%)