Protein Alignment KLK5 and flz

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_001137622.1
• Gene: flz / 35902
• FlyBaseID: FBgn0286782
• Length: 1693
• Species: Drosophila melanogaster
• Alignment Length: 304
• Identity: 81/304 - (26%)
• Similarity: 128/304 - (42%)
• Gaps: 55/304 - (18%)

Human    32 DVSCDHPSNTVPSGSNQDLGAGAGEDARSDDSSS--------------------------RIING 70
            ||:.:...|.:..|:.  |.:..|.:.|...|:|                          ||:.|
  Fly  1390 DVNPNPSDNEIDQGAT--LSSYGGANGRKIHSTSRTLPTPNLAFHSPSTECGVRPHVKSGRIVGG 1452

Human    71 SDCDMHTQPWQAAL-------LLRPNQLYCGAVLVHPQWLLTAAHCRKKVFR---VRLGHYSLSP 125
            ........|||..:       |...|:  ||.||:..::::|||||:.....   ..:|.:.:|.
  Fly  1453 KGSTFGAYPWQVLVRESTWLGLFTKNK--CGGVLITSRYVITAAHCQPGFLASLVAVMGEFDISG 1515

Human   126 VYESGQQMFQGVKS-IPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPS-AGTKCLVS 188
            ..||.:.:.:.||. |.|..|......|||.|::|:..::....:.||.:.:.... .|....|:
  Fly  1516 DLESKRSVTKNVKRVIVHRQYDPATFENDLALLELDSPVQFDTHIVPICMPNDVADFTGRMATVT 1580

Human   189 GWGTTKSPQVHFPKVLQCLNISVLSQKRCED-----AYPRQIDDTMFCAGDKAG-RDSCQGDSGG 247
            |||..|... ..|.|||.:.:.::....|::     .:.::|..:..|||...| :|||:|||||
  Fly  1581 GWGRLKYGG-GVPSVLQEVQVPIIENSVCQEMFHTAGHNKKILTSFLCAGYANGQKDSCEGDSGG 1644

Human   248 PVVCNG-----SLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQ 286
            |:|...     .|.|.||.| ..||.|..||||.....:..|::
  Fly  1645 PLVLQRPDGRYELAGTVSHG-IKCAAPYLPGVYMRTTFYKPWLR 1687

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		8/56 (14%)
		Tryp_SPc	66..285	CDD:214473	71/241 (29%)
flz	NP_001137622.1	PRK11633	<365..>439	CDD:236940
		PRK10263	<547..>1005	CDD:236669
		PHA03247	<792..1096	CDD:223021
		Tryp_SPc	1449..1689	CDD:238113	71/243 (29%)