Protein Alignment KLK5 and Corin

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_610297.2
• Gene: Corin / 35691
• FlyBaseID: FBgn0033192
• Length: 1397
• Species: Drosophila melanogaster
• Alignment Length: 267
• Identity: 89/267 - (33%)
• Similarity: 137/267 - (51%)
• Gaps: 53/267 - (19%)

Human    64 SSRIINGSDCDMHTQPWQAALLLRPNQL-YCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLSPVY 127
            |.|||.|:.......|:.||:|..|.:: ||..||:..||:|||:||        :|:||:..:.
  Fly  1101 SRRIIGGTQASPGNWPFLAAILGGPEKIFYCAGVLISDQWVLTASHC--------VGNYSVIDLE 1157

Human   128 E---------------SGQQMFQGVKS-IPHPGYSHP-GHSNDLMLIKLNRRIRPTKDVRPINVS 175
            :               |||::  .||: ||||.|:.. .|.||:.|.:|..|:...:.:.|:
  Fly  1158 DWTIQLGVTRRNSFTYSGQKV--KVKAVIPHPQYNMAIAHDNDIALFQLATRVAFHEHLLPV--- 1217

Human   176 SHC---PSA-----GTKCLVSGWG--TTKSPQVHFPKVLQCLNISVLSQKRCEDAYPR-QIDDTM 229
              |   ||.     ||.|.|.|||  ..|.|:..:..::..:.:.::::.:|::.... .:.:.|
  Fly  1218 --CLPPPSVRNLHPGTLCTVIGWGKREDKDPKSTYEYIVNEVQVPIITRNQCDEWLDNLTVSEGM 1280

Human   230 FCAG-DKAGRDSCQGDSGGPVVC-------NGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQ 286
            .||| |..|:|:||||||||::|       ...:.|:|||| ..||.|..||||.|:.::..|||
  Fly  1281 VCAGFDDGGKDACQGDSGGPLLCPYPGEKNRWFVGGIVSWG-IMCAHPRLPGVYANVVQYVPWIQ 1344

Human   287 ETIQANS 293
            |.|..:|
  Fly  1345 EQIAKHS 1351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		2/3 (67%)
		Tryp_SPc	66..285	CDD:214473	82/255 (32%)
Corin	NP_610297.2	CRD_FZ	778..894	CDD:143549
		LDLa	911..942	CDD:238060
		LDLa	945..979	CDD:238060
		SR	980..>1034	CDD:214555
		Tryp_SPc	1104..1346	CDD:238113	84/257 (33%)