Protein Alignment KLK5 and Send2

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_609708.2
• Gene: Send2 / 34836
• FlyBaseID: FBgn0264253
• Length: 239
• Species: Drosophila melanogaster
• Alignment Length: 244
• Identity: 76/244 - (31%)
• Similarity: 120/244 - (49%)
• Gaps: 29/244 - (11%)

Human    54 AGEDARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHC-RKKVFRVR 117
            ||...|.::   |||.|....:...|||.: :.|..:..||..:.....::||||| :.:.::||
  Fly    17 AGPVIRPEE---RIIGGQPIGIEEAPWQVS-IQRDGKHLCGGSIYSADIIITAAHCVQGQGYQVR 77

Human   118 LGHYSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSAG 182
            .|    |.:..|...:.. |.:|    .:|.|..||:.:::|::.:..|..|:||.::...|..|
  Fly    78 AG----SALKNSNGSVVD-VAAI----RTHEGLGNDIAIVRLSKPLEFTNQVQPIPLAKTNPPPG 133

Human   183 TKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDSCQGDSGG 247
            :...|||||:  |.....|..||.:|:.:.....|....|.:|     ||| ..||.:|:|||||
  Fly   134 SIAFVSGWGS--SSYYSHPIDLQGVNLYIQWPYYCGLTEPSRI-----CAG-SFGRAACKGDSGG 190

Human   248 PVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKW----IQETIQAN 292
            |:|.:..|.|:||.|...|...:   :||::..|.:|    |.|.:.||
  Fly   191 PLVFDQQLVGVVSGGTKDCTYSS---IYTSVPYFREWILNAIDEIMSAN 236

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		4/13 (31%)
		Tryp_SPc	66..285	CDD:214473	69/223 (31%)
Send2	NP_609708.2	Tryp_SPc	26..225	CDD:214473	68/219 (31%)