Protein Alignment KLK5 and Try29F

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_523518.2
• Gene: Try29F / 34226
• FlyBaseID: FBgn0015316
• Length: 267
• Species: Drosophila melanogaster
• Alignment Length: 251
• Identity: 91/251 - (36%)
• Similarity: 127/251 - (50%)
• Gaps: 27/251 - (10%)

Human    47 NQDLGAGAGEDARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRK 111
            |..|||    ..|......||:.|...::...|:|.:  |:.:..:||..|:...|:||||||.:
  Fly    26 NLSLGA----TVRRPRLDGRIVGGQVANIKDIPYQVS--LQRSYHFCGGSLIAQGWVLTAAHCTE 84

Human   112 ----KVFRVRLGHYSLSPVYESGQQMFQGVKSI-PHPGYSHPGHSNDLMLIKLNRRIRPTKDVRP 171
                .:.:||:|....|    .|.|:. |:|.: .||.:.......|..|::|..  ...|:|..
  Fly    85 GSAILLSKVRIGSSRTS----VGGQLV-GIKRVHRHPKFDAYTIDFDFSLLELEE--YSAKNVTQ 142

Human   172 INVSSHCPSA----GTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPR--QIDDTMF 230
            ..|......|    ||..||||||.|:|.| ....||:.:.:..:||.:|.:||..  .|.|.|.
  Fly   143 AFVGLPEQDADIADGTPVLVSGWGNTQSAQ-ETSAVLRSVTVPKVSQTQCTEAYGNFGSITDRML 206

Human   231 CAG-DKAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWI 285
            ||| .:.|:|:||||||||:..:|.|.|:|||| |.|||||.||||:.:.....||
  Fly   207 CAGLPEGGKDACQGDSGGPLAADGVLWGVVSWG-YGCARPNYPGVYSRVSAVRDWI 261

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		6/20 (30%)
		Tryp_SPc	66..285	CDD:214473	84/230 (37%)
Try29F	NP_523518.2	Tryp_SPc	42..264	CDD:238113	85/231 (37%)