Protein Alignment KLK5 and CG3355

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_608848.1
• Gene: CG3355 / 33667
• FlyBaseID: FBgn0031619
• Length: 314
• Species: Drosophila melanogaster
• Alignment Length: 243
• Identity: 81/243 - (33%)
• Similarity: 128/243 - (52%)
• Gaps: 32/243 - (13%)

Human    65 SRIINGSDCDMHTQPWQAALLLRPN--QLYCGAVLVHPQWLLTAAHC---RKKVFRVRLGHYSLS 124
            :||:.|.....:..||.|.|:...:  :|:||..|::.:::||||||   .:....:|     |.
  Fly    74 NRIVGGQQVRSNKYPWTAQLVKGRHYPRLFCGGSLINDRYVLTAAHCVHGNRDQITIR-----LL 133

Human   125 PVYESGQQ---MFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHC-PSA---- 181
            .:..|.:.   :.:.|::..||.|......||:.|:||...:..|.::||:     | |.|
  Fly   134 QIDRSSRDPGIVRKVVQTTVHPNYDPNRIVNDVALLKLESPVPLTGNMRPV-----CLPEANHNF 193

Human   182 -GTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRC-EDAYPRQIDDTMFCAG--DKAGRDSCQ 242
             |...:|:|||..|...| ....||.:|:.|::..:| :..|..:|.:.|.|||  .:.|:|:||
  Fly   194 DGKTAVVAGWGLIKEGGV-TSNYLQEVNVPVITNAQCRQTRYKDKIAEVMLCAGLVQQGGKDACQ 257

Human   243 GDSGGPVVCNG---SLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQE 287
            ||||||::.|.   .|.|:||:| |.||:.|.||||..:.||..||::
  Fly   258 GDSGGPLIVNEGRYKLAGVVSFG-YGCAQKNAPGVYARVSKFLDWIRK 304

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		1/2 (50%)
		Tryp_SPc	66..285	CDD:214473	79/238 (33%)
CG3355	NP_608848.1	Tryp_SPc	76..305	CDD:238113	80/241 (33%)