Protein Alignment KLK5 and CG4271

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_608665.1
• Gene: CG4271 / 33410
• FlyBaseID: FBgn0031409
• Length: 242
• Species: Drosophila melanogaster
• Alignment Length: 235
• Identity: 58/235 - (24%)
• Similarity: 100/235 - (42%)
• Gaps: 20/235 - (8%)

Human    63 SSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRK----KVFRVRLGHYSL 123
            ||:.|.||.:.......:.|::.: .....||..::..:.:||||.|.|    |...||:|
  Fly    15 SSNGIYNGVEAKFDFWTFLASVWV-SGYHECGGAVIDSRIVLTAAQCVKNKPVKRITVRVG---- 74

Human   124 SPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNR---RIRPTKDVRPINVSSHCPSAGTKC 185
            :|....|.::.:....:.|..|.:  ..||:.|:.|.:   .:|.||    |.:::..||.....
  Fly    75 TPDIYRGGRIIRVTALVVHENYKN--WDNDIALLWLEKPVLSVRVTK----IPLATKEPSENEYP 133

Human   186 LVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDSCQGDSGGPVV 250
            ..:|||..........:.||.....:..:..|.:.....:.:.:.|| .....|.|.||.|||:|
  Fly   134 SNAGWGEKLLESYVVTRKLQNGVTKIRPRSMCAEELVEPVGEELLCA-FYTENDICPGDYGGPLV 197

Human   251 CNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQ 290
            ....:.|:...| :.|.....|.:|||:..:.:||:|..:
  Fly   198 LANKVVGIAVQG-HGCGFAVLPSLYTNVFHYLEWIEENAE 236

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		2/4 (50%)
		Tryp_SPc	66..285	CDD:214473	53/225 (24%)
CG4271	NP_608665.1	Tryp_SPc	19..234	CDD:238113	55/227 (24%)