Protein Alignment KLK5 and Send1

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_608662.1
• Gene: Send1 / 33407
• FlyBaseID: FBgn0031406
• Length: 255
• Species: Drosophila melanogaster
• Alignment Length: 238
• Identity: 72/238 - (30%)
• Similarity: 118/238 - (49%)
• Gaps: 29/238 - (12%)

Human    62 DSSSRIINGSDCDMHTQPWQAALLLRPNQLY----CGAVLVHPQWLLTAAHCRKKVFR-VRLGHY 121
            :.|.|||.||..|:...|||.:|     |.|    ||..:.....::|||||.|:..| :|.|
  Fly    25 EPSERIIGGSSMDITDVPWQVSL-----QYYGEHFCGGSIYSKTIIITAAHCIKEGERSIRAG-- 82

Human   122 SLSPVYESGQQMFQGVKS-IPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSAGTKC 185
              |.:::|| .:..||:: |.||.:......||:.::||:..:..:..::.|.::...|...:..
  Fly    83 --SSLHDSG-GVVVGVEAYIIHPQFDKHNMENDVAVLKLSSPLSFSDSIQTIPLAETDPPTSSSA 144

Human   186 LVSGWGTTKSPQVHF---PKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDSCQGDSGG 247
            |.:|||     :.:|   |:.||.:.|.:.....|:..|...:.:...||| :.|:..|.|||||
  Fly   145 LATGWG-----RGNFLIRPRQLQGVEILIRPLIVCKLKYGNGVFNEDICAG-RMGKGGCYGDSGG 203

Human   248 PVVCNGSLQGLVS-WGDYPCARPNRPGVYTNLCKFTKWIQETI 289
            |:|.||.|.|:.| .|:..|...:   :|.::.::..||...|
  Fly   204 PLVFNGQLVGITSRTGNIVCLGSS---LYASVARYRNWILSAI 243

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		2/5 (40%)
		Tryp_SPc	66..285	CDD:214473	68/228 (30%)
Send1	NP_608662.1	Tryp_SPc	29..239	CDD:214473	68/228 (30%)