Protein Alignment KLK5 and CG11911

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_608518.1
• Gene: CG11911 / 33206
• FlyBaseID: FBgn0031249
• Length: 277
• Species: Drosophila melanogaster
• Alignment Length: 257
• Identity: 69/257 - (26%)
• Similarity: 119/257 - (46%)
• Gaps: 30/257 - (11%)

Human    54 AGEDARSDDSSSR---------IINGSDCDMHTQPWQAAL---LLRPNQLYCGAVLVHPQWLLTA 106
            |.:.|:..|..::         :|||::.:.|:.|:..:|   .|:.:.: ||..|::..|::||
  Fly    15 AAQGAKLSDKLAKLVPSFATGFVINGTEAEPHSAPYIVSLATNYLKHSHI-CGGTLINKDWIVTA 78

Human   107 AHCRKKVFRVRL--GHYSLSPVYESGQQM---FQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPT 166
            |||..:...:.:  |.::.:.|.|..||.   |..|    |..|:......|:.|:.:|......
  Fly    79 AHCISEPVGMSIIAGLHTRAEVDELTQQRQVDFGRV----HEKYTGGVGPYDIALLHVNESFIFN 139

Human   167 KDVRPINVSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQ--IDDTM 229
            :.|:|..:.|.......:..:.|||..||......|.||.:...:|:.:.|::..|..  |.::.
  Fly   140 EWVQPATLPSREQVHEGETHLYGWGQPKSYIFSGAKTLQTVTTQILNYEECKEELPESAPIAESN 204

Human   230 FCAGD-KAGRDSCQGDSGGPVVCN-----GSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWI 285
            .|:.. :..:.:|.||||||:|..     ..|.|:||||..||...|.|.:||.:..:..||
  Fly   205 ICSSSLQQSKSACNGDSGGPLVVEFTNAPSELIGIVSWGYIPCGLANMPSIYTKVSAYIDWI 266

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		3/22 (14%)
		Tryp_SPc	66..285	CDD:214473	64/243 (26%)
CG11911	NP_608518.1	Tryp_SPc	37..266	CDD:214473	64/233 (27%)