Protein Alignment KLK5 and CG11912

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_608517.1
• Gene: CG11912 / 33205
• FlyBaseID: FBgn0031248
• Length: 271
• Species: Drosophila melanogaster
• Alignment Length: 259
• Identity: 72/259 - (27%)
• Similarity: 102/259 - (39%)
• Gaps: 50/259 - (19%)

Human    66 RIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLSPVYESG 130
            |||||.:......|:..:|....|..:|...|:....::|||||.               .|..|
  Fly    29 RIINGYEAAKGEAPYIVSLQTTSNSHFCAGSLLDEVTIVTAAHCL---------------TYNQG 78

Human   131 Q----------------QMFQGVKSIPHPGYSHPGHSND--LMLIK------LNRRIRP-TKDVR 170
            |                :.|...:.:.|..|......||  |:|:|      ||...|. :..|.
  Fly    79 QAVAGAHSRTDQENVQIRKFTNAQYVIHENYGGGVGPNDIGLILLKEEDAFDLNAVARDGSNPVS 143

Human   171 PINVSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYP--RQIDDTMFCAG 233
            .:::.|......:...:.|||...|..:  |..||.|:..::....|:.|.|  ..:.:|..|..
  Fly   144 AVSLPSKTFQGTSDGYLYGWGRDNSGLL--PLNLQKLDAIIVDYNECKAALPSNNSLAETNVCTH 206

Human   234 DKAGRD-SCQGDSGGPVVCNGS-----LQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQA 291
            .....| ||.||||||:|...|     |.|:||||..||.....|.|||::..|..||.|..:|
  Fly   207 TPGKADGSCNGDSGGPLVSQSSSRGAELIGIVSWGYTPCLSTTYPSVYTSVSSFLPWIDENRKA 270

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		1/1 (100%)
		Tryp_SPc	66..285	CDD:214473	68/251 (27%)
CG11912	NP_608517.1	Tryp_SPc	29..264	CDD:214473	68/251 (27%)