Protein Alignment KLK5 and CG1304

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_608418.1
• Gene: CG1304 / 33074
• FlyBaseID: FBgn0031141
• Length: 260
• Species: Drosophila melanogaster
• Alignment Length: 282
• Identity: 69/282 - (24%)
• Similarity: 115/282 - (40%)
• Gaps: 47/282 - (16%)

Human    18 ALLLGVTEHVLANNDVSCDHPSNTVPSGSNQDLGAGAGEDARSDDSSSRIINGSDCDMHTQPWQA 82
            |:|||....:||       .|.::.|...|                 .|::.|.|...:..|.|.
  Fly     7 AILLGSFLLLLA-------VPVHSAPGSLN-----------------GRVVGGEDAVKNQFPHQV 47

Human    83 ALLLRPNQLYCGAVLVHPQWLLTAAHC-------------RKKVFRVRLGHYSLSPVYESGQQMF 134
            : |.......||..::...::||||||             ..:.|.:|.|    |....||..:.
  Fly    48 S-LRNAGSHSCGGSILSRNYVLTAAHCVTNQDSNGNSVPIAAERFTIRAG----SNDRFSGGVLV 107

Human   135 QGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSAGTKCLVSGWGTTKSPQVH 199
            |..:.|.|..|.:  ..||:.|::|...:..:..::||::.:....|....::||||..|. |..
  Fly   108 QVAEVIVHEEYGN--FLNDVALLRLESPLILSASIQPIDLPTADTPADVDVIISGWGRIKH-QGD 169

Human   200 FPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDSCQGDSGGPVVCNGSLQGLVSWGDY 264
            .|:.||...:..:|.:||::.....:...: |...:|...:|.||||||.|.|..:.|:..:...
  Fly   170 LPRYLQYNTLKSISLERCDELIGWGVQSEL-CLIHEADNGACNGDSGGPAVYNNQVVGVAGFVWS 233

Human   265 PCARPNRPGVYTNLCKFTKWIQ 286
            .|. .:.|..|..:....:||:
  Fly   234 ACG-TSYPDGYARVYYHNEWIK 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		4/30 (13%)
		Tryp_SPc	66..285	CDD:214473	58/231 (25%)
CG1304	NP_608418.1	Tryp_SPc	32..256	CDD:238113	59/233 (25%)